
CAS 214193-10-9
:N-Boc-L-trans-4,5-methanoproline ethyl ester
Description:
N-Boc-L-trans-4,5-methanoproline ethyl ester is a chemical compound characterized by its unique structure, which includes a bicyclic proline derivative. The "N-Boc" (tert-butoxycarbonyl) group serves as a protecting group for the amine, enhancing the compound's stability and solubility in organic solvents. This compound features a trans configuration at the 4 and 5 positions of the proline ring, which is significant for its conformational properties and potential biological activity. The ethyl ester moiety contributes to its lipophilicity, making it suitable for various synthetic applications, particularly in peptide synthesis and drug development. The compound is typically used in research settings, especially in the fields of medicinal chemistry and biochemistry, due to its ability to mimic natural amino acids while providing unique reactivity. Its CAS number, 214193-10-9, allows for easy identification and retrieval of information regarding its properties and applications in scientific literature. Overall, N-Boc-L-trans-4,5-methanoproline ethyl ester is a valuable intermediate in the synthesis of more complex molecules.
Formula:C13H21NO4
Synonyms:- O2-tert-butyl O3-ethyl (1R,3S,5R)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate
- N-Boc-L-trans-4,5-methanoproline ethyl ester
- Saxagliptin Impurity 47
- 2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester, (1R,3S,5R)-
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Found 3 products.
N-Boc-L-trans-4,5-methanoproline Ethyl Ester
CAS:Controlled Product<p>Applications N-Boc-L-trans-4,5-methanoproline Ethyl Ester is an impurity of the drug Saxagliptin (S143500), a potent and selective reversible inhibitor of dipeptidyl peptidase-4.<br>References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),<br></p>Formula:C13H21NO4Color and Shape:NeatMolecular weight:255.31


