CAS 214630-02-1

Boc-D-Arg(Pmc)-OH

Description:

Boc-D-Arg(Pmc)-OH, with the CAS number 214630-02-1, is a protected amino acid derivative commonly used in peptide synthesis. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions without interference from the amine. The "D-Arg" indicates that the amino acid is in its D-enantiomer form, which can be important for specific biological activity or structural properties. The "Pmc" (2,2,5,5-tetramethyl-1-pyrrolidinyl) group is another protective moiety that shields the side chain of arginine, facilitating the synthesis of peptides while preventing unwanted reactions. This compound is typically white to off-white in appearance and is soluble in organic solvents, making it suitable for various synthetic applications. Its stability under standard laboratory conditions allows for ease of handling, while its specific functional groups enable the formation of peptide bonds in the synthesis of more complex molecules. Overall, Boc-D-Arg(Pmc)-OH is a valuable intermediate in the field of medicinal chemistry and peptide research.

Formula: C₂₅H₄₀N₄O₇S

Synonyms:

• Boc-D-Arginine(Pmc)-Oh
• Boc-N-Omega-(2,2,4,6,7-Pentamethylchroman-6-Sulfonyl)-D-Arginine
• N-Alpha-T-Butoxycarbonyl-N-Omega-(2,2,5,7,8-Pentamethylchroman-6-Sulfonyl)-D-Arginine
• D-Ornithine, N5-[[[(3,4-Dihydro-2,2,5,7,8-Pentamethyl-2H-1-Benzopyran-6-Yl)Sulfonyl]Amino]Iminomethyl]-N2-[(1,1-Dimethylethoxy)Carbonyl]-

Boc-D-Arg(Pmc)-OH

CAS: 214630-02-1

Bachem ID: 4027638.

Formula: C₂₅H₄₀N₄O₇S

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 540.69

Ref: 01-4027638

Boc-D-Arg(Pmc)-OH

CAS: 214630-02-1

Boc-D-Arg(Pmc)-OH is a triazole derivative that inhibits the production of proinflammatory cytokines. It is used as a therapeutic for premature infants to reduce the risk of infections, such as sepsis and meningitis. Boc-D-Arg(Pmc)-OH has been shown to inhibit interleukin 1 receptor (IL1R) and IL1β synthesis in human cells. Boc-D-Arg(Pmc)-OH binds to the triazole ring of IL1β, preventing the formation of an enzyme complex that is required for IL1β synthesis. This binding also prevents the formation of an enzyme complex that is required for IL1R synthesis. The conformation of the peptide chain may be important for its activity, with some stereoisomers being more potent than others.

Formula: C₂₅H₄₀N₄O₇S

Purity: Min. 95%

Molecular weight: 540.67 g/mol

Ref: 3D-FB111262