CAS 214750-76-2

(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopropanepropanoic acid

Description:

The chemical substance known as (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopropanepropanoic acid, with the CAS number 214750-76-2, is a synthetic amino acid derivative. It features a cyclopropane ring, which contributes to its unique structural properties and potential biological activity. The presence of the fluorenylmethoxycarbonyl (Fmoc) group indicates that this compound is likely used in peptide synthesis as a protective group for amino acids, facilitating the formation of peptide bonds while preventing unwanted reactions. The stereochemistry denoted by (αS) suggests that it has a specific spatial arrangement, which can influence its interaction with biological targets, such as enzymes or receptors. This compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. Its solubility, stability, and reactivity will depend on the specific functional groups present and the overall molecular structure, which can affect its application in various chemical and biological contexts.

Formula: C₂₁H₂₁NO₄

InChI: InChI=1S/C21H21NO4/c23-20(24)19(11-13-9-10-13)22-21(25)26-12-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,13,18-19H,9-12H2,(H,22,25)(H,23,24)/t19-/m0/s1

InChI key: InChIKey=DRGUEWQZLABTFG-IBGZPJMESA-N

SMILES: C(OC(N[C@@H](CC1CC1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• (2S)-3-Cyclopropyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• (2S)-3-Cyclopropyl-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
• (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopropanepropanoic acid
• Cyclopropanepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αS)-
• Fmoc-(S)-3-Cyclopropylalanine
• Fmoc-L-Cyclopropylalanine
• Fmoc-β-Cyclopropyl-L-Alanine
• FMOC-ALA(CYCLOPROPYL)-OH
• FMOC-BETA-CYCLOPROPYL-L-ALA-OH
• FMOC-ALA-BETA-CYCLOPROPYL-OH
• FMOC-L-ALA(3-CYCLOPROPYL)
• FMOC-BETA-CYCLOPROPYL-ALA-OH
• N-FMOC-BETA-CYCLOPROPYL-L-ALANINE
• FMOC-L-CPA-OH
• N-FMOC-CYCLOPROPYL ALANINE
• N-ALPHA-FMOC-BETA-CYCLOPROPYL-L-ALANINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE
• 3-CYCLOPROPYL-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID
• FMOC-ALA(CPRO)-OH
• FMOC-BETA-CYCLOPROPYL-L-ALANINE
• Fmoc-b-cyclopropyl-L-Ala-OH
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-CYCLOPROPYL-L-ALANINE

Fmoc-β-cyclopropyl-Ala-OH

CAS: 214750-76-2

Bachem ID: 4027349.

Formula: C₂₁H₂₁NO₄

Purity: 99.1%

Color and Shape: White Powder

Molecular weight: 351.4

Ref: 01-4027349

Fmoc-(S)-3-Cyclopropylalanine

CAS: 214750-76-2

Fmoc-(S)-3-Cyclopropylalanine

Formula: C₂₁H₂₁NO₄

Purity: 95%

Molecular weight: 351.39574

Ref: 54-OR451117

Fmoc-β-cyclopropyl-L-Alanine

CAS: 214750-76-2

Formula: C₂₁H₂₁NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 351.3957

Ref: IN-DA007169

Fmoc-β-cyclopropyl-L-Ala-OH

CAS: 214750-76-2

Formula: C₂₁H₂₁NO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 351.4

Ref: 7W-GM3114

N-Fmoc-cyclopropyl alanine

CAS: 214750-76-2

Formula: C₂₁H₂₁NO₄

Purity: 97%

Color and Shape: White to off-white powder

Molecular weight: 351.402

Ref: 10-F041310

Fmoc-L-cyclopropylalanine

Controlled Product

CAS: 214750-76-2

Applications Fmoc-L-cyclopropylalanine is used to develop low molecular weight HIV-1 protease dimerization inhibitors. It is also used to prepare piperazinone derivatives as a novel class of potent HCV NS4B inhibitors.
References Hwang, Y., et al.: J. Med. Chem., 48, 2239 (2005); Kakaria, R., et al.: J. Med. Chem., 57, 2136 (2014)

Formula: C₂₁H₂₁NO₄

Color and Shape: Neat

Molecular weight: 351.4

Ref: TR-F622780