CAS 2152-34-3

Pemoline

Description:

Pemoline is a central nervous system stimulant that was primarily used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is classified as a pyrimidine derivative and is known for its ability to enhance cognitive function and alertness. Pemoline acts by increasing the levels of certain neurotransmitters in the brain, particularly dopamine, which plays a crucial role in attention and behavior regulation. The substance is typically administered in oral form and has a relatively long half-life, allowing for once-daily dosing in some cases. However, due to concerns about potential liver toxicity and the risk of serious side effects, its use has declined, and it is no longer widely prescribed. Pemoline is also associated with a potential for abuse, which has led to its classification as a controlled substance in some jurisdictions. Overall, while it has therapeutic applications, the safety profile and regulatory status of pemoline warrant careful consideration.

Formula: C₉H₈N₂O₂

InChI: InChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

InChI key: InChIKey=NRNCYVBFPDDJNE-UHFFFAOYSA-N

SMILES: O=C1C(OC(N)=N1)C2=CC=CC=C2

Synonyms:

• 2-Amino-5-phenyl-1,3-oxazol-4(5H)-one
• 2-Amino-5-phenyl-2-oxazolin-4-one
• 2-Amino-5-phenyl-4(5H)-oxazolone
• 2-Amino-5-phenyl-4-oxazolone
• 2-Imino-4-keto-5-phenyltetrahydrooxazole
• 2-Imino-4-oxo-5-phenyloxazolidine
• 2-Imino-5-phenyl-4-oxazolidinone
• 2-Inino-5-phenyloxazolidin-4-one
• 2-Oxazolin-4-one, 2-amino-5-phenyl-
• 4(5H)-Oxazolone, 2-amino-5-phenyl-
• 4-Oxazolidinone, 2-imino-5-phenyl-
• 5-Phenyl-2-imino-4-oxazolidinone
• 5-Phenyl-2-imino-4-oxooxazolidine
• 5-Phenyl-2-iminooxazolidin-4-one
• 5-Phenylisohydantion
• Abbott 13397
• Azoksodon
• Azoxodon
• Azoxodone
• Betanamin
• Centramin
• Constimol
• Cylert
• Dantromin
• Deltamin
• Deltamin (VAN)
• Deltamine
• Endolin
• Fenoxazol
• Fio
• Fwh-352
• Hsdb 3148
• Hyton
• Hyton Asa
• Juston-wirkstoff
• Kethamed
• La 956
• Myamin
• Nitan
• Notair
• Npl 1
• Nsc 169499
• Nsc 25159
• Okodon
• PIO
• Pemolin
• Pemolina
• Pemoline (including organometallic complexes and chelates thereof)
• Pemolinum
• Phenalone
• Phenilone
• Pheniminooxazolidinone
• Phenoxazole
• Phenylisohydantoin
• Phenylpseudohydantoin
• Pioxol
• Pomoline
• Pondex
• Pt 360
• Ronyl
• Senior
• Sigmadyn
• Sistra
• Sofro
• Stimul
• Stimulol
• Tradon
• Tradone
• Volital
• Volitol

Pemoline

Controlled Product

CAS: 2152-34-3

Color and Shape: Neat

Ref: LP-PEM-541-FB-10

4-Oxo-2-imino-5-phenyloxazlidine

Controlled Product

CAS: 2152-34-3

Formula: C₉H₈N₂O₂

Molecular weight: 176.17

Ref: 7W-GE9461

Pemoline

Controlled Product

CAS: 2152-34-3

Applications Pemoline is a CNS stimulant. Controlled Substance.
References Connors, C.K., et al.: Psychopharacolgia, 26, 321 (1972), Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972),

Formula: C₉H₈N₂O₂

Color and Shape: White To Off-White

Molecular weight: 176.17

Ref: TR-P220100

Pemoline (1 mg/mL in Methanol)

Controlled Product

CAS: 2152-34-3

Formula: C₉H₈N₂O₂

Color and Shape: Single Solution

Molecular weight: 176.17

Ref: TR-KIT2100

Pemoline

Controlled Product

CAS: 2152-34-3

Pemoline is a psychostimulant drug that increases the activity of the central nervous system. It is used in the treatment of attention deficit disorder and narcolepsy. Pemoline has been shown to have high efficacy in experimental models with humans, where it has been shown to reduce body mass index and locomotor activity. The mechanism of action for pemoline is thought to be through its interaction with dopamine receptors, although the exact receptor binding site has not yet been identified.

Formula: C₉H₈N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 176.17 g/mol

Ref: 3D-FP156788