CAS 215874-86-5

α 5IA

Description:

α 5IA, with the CAS number 215874-86-5, is a synthetic compound that belongs to the class of indole derivatives. It is primarily recognized for its potential applications in the field of pharmacology, particularly in research related to neuropharmacology and psychoactive substances. The compound exhibits a unique structure that may influence its interaction with various biological targets, including receptors in the central nervous system. Characteristically, α 5IA may demonstrate properties such as selective binding affinity, which can lead to specific physiological effects. Its solubility, stability, and reactivity are influenced by its molecular structure, making it a subject of interest for further studies aimed at understanding its mechanism of action and potential therapeutic uses. As with many synthetic compounds, safety and regulatory considerations are paramount, necessitating thorough evaluation in preclinical and clinical settings to ascertain its efficacy and safety profile.

Formula: C₁₇H₁₄N₈O₂

InChI: InChI=1S/C17H14N8O2/c1-10-7-14(22-27-10)16-20-19-15-12-5-3-4-6-13(12)17(21-25(15)16)26-9-11-8-24(2)23-18-11/h3-8H,9H2,1-2H3

InChI key: InChIKey=NZMJFRXKGUCYNP-UHFFFAOYSA-N

SMILES: O(CC=1N=NN(C)C1)C2=NN3C(C=4C2=CC=CC4)=NN=C3C5=NOC(C)=C5

Synonyms:

• 3-(5-Methyl-3-isoxazolyl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy]-1,2,4-triazolo[3,4-a]phthalazine
• 1,2,4-Triazolo[3,4-a]phthalazine, 3-(5-methyl-3-isoxazolyl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy]-
• α 5IA
• α5IA
• Α5ia (α5IA)
• 5-Methyl-3-(6-((1-Methyl-1H-1,2,3-triazol-4-yl)Methoxy)-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)isoxazole
• L822179
• L 822
• L-822
• 3-(5-Methylisoxazol-3-yl)-6-(1-methyl-1,2,3-triazol-4-yl)methoxy-1,2,4-triazolo[3,4-a]phthalazine
• 3-(5-Methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine
• L822
• a5IA
• L-822179
• L 822179
• 3-(5-Methylisoxazol-3-yl)-6-[(1-Methyl-1H-1,2,3-triazol-4-yl)Met

α5IA

CAS: 215874-86-5

Formula: C₁₇H₁₄N₈O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 362.3455

Ref: IN-DA0033GL

L-822179

CAS: 215874-86-5

L-822179

Formula: C₁₇H₁₄N₈O₂

Purity: ≥98%

Molecular weight: 362.35

Ref: 54-BUP11561

α5IA

Controlled Product

CAS: 215874-86-5

Applications Alpha5IA is an α5-selective inverse agonist which enhance cognitive performance in rodents and encouraging in human. A triazolophthalazine that selectively attentuates the effects of GABA at GABAA receptors.
References Eng, W., et al.: Neuropharmacol., 59, 635-639 (2010); Atack, J. R.: Pharmacol. Ther., 125, 11-26 (2010);

Formula: C₁₇H₁₄N₈O₂

Color and Shape: Neat

Molecular weight: 362.35

Ref: TR-I942008

3-(5-METHYLISOXAZOL-3-YL)-6-[(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)METHOXY][1,2,4]TRIAZOLO[3,4-A]PHTHALAZINE

CAS: 215874-86-5

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 362.3529968261719

Ref: 10-F386946

L-822179

CAS: 215874-86-5

L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.

Formula: C₁₇H₁₄N₈O₂

Purity: 98.5% - 99.61%

Color and Shape: White Solid

Molecular weight: 362.35

Ref: TM-T24381