CAS 2166587-77-3

Formula: C43H45N7O6S

InChI: InChI=1S/C43H45N7O6S/c1-27-10-11-30(23-44-27)39-46-28(2)37(57-39)42(53)48-16-12-34(36(24-48)29-8-6-5-7-9-29)40(51)47-18-14-43(54,15-19-47)25-49-26-45-38-35(41(49)52)13-17-50(38)31-20-32(55-3)22-33(21-31)56-4/h5-11,13,17,20-23,26,34,36,54H,12,14-16,18-19,24-25H2,1-4H3/t34-,36+/m1/s1

InChI key: JGAGTDLXPLBRCX-VHFKIGOXSA-N

SMILES: CC1=NC=C(C=C1)C2=NC(=C(S2)C(=O)N3CC[C@H]([C@@H](C3)C4=CC=CC=C4)C(=O)N5CCC(CC5)(CN6C=NC7=C(C6=O)C=CN7C8=CC(=CC(=C8)OC)OC)O)C

USP7-IN-16

CAS: 2166587-77-3

USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.

Formula: C₄₃H₄₅N₇O₆S

Color and Shape: Solid

Molecular weight: 787.93

Ref: TM-T203646