CAS 2173508-07-9

Formula: C30H32FN5O3

InChI: InChI=1S/C30H32FN5O3/c1-18-12-22(9-8-20(18)14-23-13-19(2)34-35-29(23)39)28(38)33-16-27(37)36-25(21-6-5-7-24(31)15-21)10-11-26(36)30(3,4)17-32/h5-9,12-13,15,25-26H,10-11,14,16H2,1-4H3,(H,33,38)(H,35,39)/t25-,26+/m0/s1

InChI key: BRTUOYAEDFAFHK-IZZNHLLZSA-N

SMILES: CC1=C(C=CC(=C1)C(=O)NCC(=O)N2[C@@H](CC[C@@H]2C(C)(C)C#N)C3=CC(=CC=C3)F)CC4=CC(=NNC4=O)C

CGRP antagonist 7

CAS: 2173508-07-9

CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.

Formula: C₃₀H₃₂FN₅O₃

Color and Shape: Solid

Molecular weight: 529.61

Ref: TM-T211975