
CAS 2189366-77-4
:Formula:C18H16N4O2
InChI:InChI=1S/C18H16N4O2/c1-11(22-10-12-6-2-3-7-13(12)17(22)24)16(23)21-18-19-14-8-4-5-9-15(14)20-18/h2-9,11H,10H2,1H3,(H2,19,20,21,23)/t11-/m1/s1
InChI key:PWSSISUOJZBZFT-LLVKDONJSA-N
SMILES:C[C@H](C(=O)NC1=NC2=CC=CC=C2N1)N3CC4=CC=CC=C4C3=O
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Ltβr-in-1
CAS:Ltβr-in-1 is a novel protein that belongs to the lipocalin family. It is expressed in the cytoplasm and binds to the carboxyl-terminal domain of Ltβr, which is a GPCR. Binding of Ltβr-in-1 in the cytoplasm inhibits p65 nuclear translocation and transcriptional regulation mediated by the NF-κB pathway. This protein has been shown to have anti-cancer activity by inducing necrosis and inhibiting cell proliferation. It also reduces inflammation by downregulating TNF-α transcription.Formula:C18H16N4O2Purity:Min. 95%Molecular weight:320.3 g/molLTβR-IN-1
CAS:LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.Formula:C18H16N4O2Purity:98.93%Color and Shape:White SolidMolecular weight:320.3452




