CAS 219137-85-6

L-a-Asparagine,N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-(9CI)

Description:

L-a-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl] is a complex organic compound characterized by its unique structure, which includes an amino acid backbone and a benzopyran moiety. This compound features a combination of amino acids, specifically L-asparagine, L-tyrosine, L-valine, and L-alanine, which contribute to its potential biological activity. The presence of the N-acetyl group suggests modifications that may enhance solubility or stability. The trifluoromethyl group and the benzopyran structure indicate potential pharmacological properties, as these functional groups are often associated with increased lipophilicity and biological activity. The compound's CAS number, 219137-85-6, allows for precise identification in chemical databases. Overall, this substance may be of interest in medicinal chemistry and drug development due to its structural complexity and the potential interactions of its various functional groups. Further studies would be necessary to elucidate its specific properties and applications.

Formula: C₃₃H₃₆F₃N₅O₁₀

Synonyms:

• N-Acetyl-Tyr-Val-Ala-Asp 7-Amido-4-Trifluoromethylcoumarin
• Caspase-1 Substrate Xii, Fluorogenic
• Caspase 1 (Ice) Substrate 2F, Fluorogenic
• Ac-Yvad-Afc
• Ac-Tyr-Val-Ala-Asp-7-Amino-4-Trifluoromethyl Coumarin
• Ac-Tyr-Val-Ala-Asp-Afc
• N-Acetyl-Tyr-Val-Ala-Asp-(7-amino-4-trifluoromethylcoumarin)

Ac-Tyr-Val-Ala-Asp-AFC

CAS: 219137-85-6

The presence of halogen substituents at the fluorescent group improves membrane permeability of the YVAD-derived caspase-1 substrate.

Formula: C₃₃H₃₆F₃N₅O₁₀

Purity: 98.5%

Molecular weight: 719.67

Ref: 01-4027522

Ac-YVAD-AFC

CAS: 219137-85-6

Formula: C₃₃H₃₆F₃N₅O₁₀

Purity: 97%

Color and Shape: Solid

Molecular weight: 719.6616

Ref: IN-DA00BCJ9

Ac-YVAD-AFC

CAS: 219137-85-6

Ac-YVAD-AFC

Formula: C₃₃H₃₆F₃N₅O₁₀

Purity: ≥98%

Molecular weight: 719.66

Ref: 54-BUP21486

Ac-YVAD-AFC

CAS: 219137-85-6

Ac-YVAD-AFC is a fluorescent peptide substrate used to detect caspase-1. When cleaved, it releases the fluorescent molecule AFC

Formula: C₃₃H₃₆F₃N₅O₁₀

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 719.66

Ref: TM-T78431

N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin

Controlled Product

CAS: 219137-85-6

Applications N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin is a substrate whose amino acids are shown as a preferred cleavage site for Caspase-1 and 4. Useful for caspase research.
References Talanian, R. et al.: J. Biol. Chem., 272, 9677 (1977); Marcelli, M. et al.: Cancer Res., 58, 76 (1998);

Formula: C₃₃H₃₆F₃N₅O₁₀

Color and Shape: Neat

Molecular weight: 719.67

Ref: TR-A189765