CymitQuimica logo

CAS 2202738-42-7

:

USP7-IN-3

Description:
USP7-IN-3, identified by its CAS number 2202738-42-7, is a small molecule inhibitor specifically targeting the ubiquitin-specific protease 7 (USP7), an enzyme involved in various cellular processes, including protein degradation and regulation of signaling pathways. This compound is characterized by its potential therapeutic applications in cancer treatment and other diseases where USP7 plays a critical role in tumorigenesis and cell survival. USP7-IN-3 is typically evaluated for its potency, selectivity, and pharmacokinetic properties, which are crucial for its efficacy as a drug candidate. The compound's structure includes specific functional groups that facilitate its interaction with the active site of USP7, thereby inhibiting its enzymatic activity. Research into USP7-IN-3 also focuses on its safety profile and potential side effects, which are essential considerations in drug development. Overall, USP7-IN-3 represents a promising avenue for therapeutic intervention in diseases associated with dysregulated ubiquitin-proteasome pathways.
Formula:C29H31F3N6O3
InChI:InChI=1S/C29H31F3N6O3/c1-36-26(21-9-7-19(16-33)8-10-21)24-25(35-36)27(40)38(18-34-24)17-28(41)11-13-37(14-12-28)23(39)15-22(29(30,31)32)20-5-3-2-4-6-20/h2-10,18,22,41H,11-17,33H2,1H3/t22-/m1/s1
InChI key:RLPQYKGBXQQARM-JOCHJYFZSA-N
SMILES:CN1C(=C2C(=N1)C(=O)N(C=N2)CC3(CCN(CC3)C(=O)C[C@H](C4=CC=CC=C4)C(F)(F)F)O)C5=CC=C(C=C5)CN
Synonyms:
  • 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 3-[4-(aminomethyl)phenyl]-2,6-dihydro-6-[[4-hydroxy-1-[(3R)-4,4,4-trifluoro-1-oxo-3-phenylbutyl]-4-piperidinyl]methyl]-2-methyl-
  • USP7-IN-3
Found 4 products.