CAS 2206827-14-5

Sorafenib Isopropyl Carbamate (Isopropyl {4-[2-(methylcarbamoyl)pyridin-4-yl]oxyphenyl}carbamate)

CAS: 2206827-14-5

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₁₉N₃O₄

Color and Shape: Off-White Powder

Molecular weight: 329.13756

Ref: 45-1A06360

Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate

CAS: 2206827-14-5

Formula: C₁₇H₁₉N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 329.3505

Ref: IN-DA024I4O

Sorafenib EP Impurity D

CAS: 2206827-14-5

Formula: C₁₇H₁₉N₃O₄

Color and Shape: Yellow Solid

Molecular weight: 329.36

Ref: 4Z-S-2711

Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate

CAS: 2206827-14-5

Applications Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate is an impurity in the synthesis of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),

Formula: C₁₇H₁₉N₃O₄

Color and Shape: Neat

Molecular weight: 329.35

Ref: TR-I872280

Sorafenib EP Impurity D

CAS: 2206827-14-5

Formula: C₁₇H₁₉N₃O₄

Molecular weight: 329.36

Ref: ST-EA-CP-S16004