CAS 2206827-14-5

Formula: C17H19N3O4

InChI: InChI=1S/C17H19N3O4/c1-11(2)23-17(22)20-12-4-6-13(7-5-12)24-14-8-9-19-15(10-14)16(21)18-3/h4-11H,1-3H3,(H,18,21)(H,20,22)

InChI key: OTZYFALTTCYAFP-UHFFFAOYSA-N

SMILES: CC(C)OC(=O)NC1=CC=C(C=C1)OC2=CC(=NC=C2)C(=O)NC

Sorafenib Isopropyl Carbamate

CAS: 2206827-14-5

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₁₉N₃O₄

Color and Shape: Off-White Powder

Molecular weight: 329.13756

Ref: 45-1A06360

1-Methylethyl N-[4-[[2-[(methylamino)carbonyl]-4-pyridinyl]oxy]phenyl]carbamate

CAS: 2206827-14-5

Formula: C₁₇H₁₉N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 329.3505

Ref: IN-DA024I4O

Sorafenib EP Impurity D (Sorafenib Isopropyl Carbamate)

CAS: 2206827-14-5

Formula: C₁₇H₁₉N₃O₄

Color and Shape: Yellow Solid

Molecular weight: 329.36

Ref: 4Z-S-2711

Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate

CAS: 2206827-14-5

Applications Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate is an impurity in the synthesis of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),

Formula: C₁₇H₁₉N₃O₄

Color and Shape: Neat

Molecular weight: 329.35

Ref: TR-I872280

Sorafenib EP Impurity D

CAS: 2206827-14-5

Formula: C₁₇H₁₉N₃O₄

Molecular weight: 329.36

Ref: ST-EA-CP-S16004