CAS 220904-83-6

3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one

Description:

3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one, with the CAS number 220904-83-6, is a synthetic organic compound characterized by its complex structure, which includes a dihydroindole core and multiple halogen substituents. The presence of bromine and iodine atoms contributes to its unique reactivity and potential biological activity. The hydroxyl group on the benzylidene moiety may enhance its solubility in polar solvents and influence its interaction with biological targets. This compound is likely to exhibit interesting properties such as fluorescence or photochemical behavior due to the conjugated system formed by the indole and benzylidene components. Its structural features suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals or as a probe in biochemical studies. However, detailed studies on its toxicity, stability, and specific biological activities would be necessary to fully understand its potential uses and safety profile.

Formula: C₁₅H₈Br₂INO₂

InChI: InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)

InChI key: InChIKey=LMXYVLFTZRPNRV-UHFFFAOYSA-N

SMILES: C(=C1C=2C(NC1=O)=CC=C(I)C2)C3=CC(Br)=C(O)C(Br)=C3

Synonyms:

• (3Z)-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1,3-dihydro-2H-indol-2-one
• 2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-
• 3-(3,5-Dibromo-4-Hydroxybenzylidene)-5-Iodoindolin-2-One
• 3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
• 3-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one
• Gw-5074
• Gw5074
• MG 005

GW-5074

CAS: 220904-83-6

Formula: C₁₅H₈Br₂INO₂

Purity: >95.0%(HPLC)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 520.95

Ref: 3B-G0609

GW 5074

CAS: 220904-83-6

Formula: C₁₅H₈Br₂INO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 520.9420

Ref: IN-DA007PMS

GW 5074

CAS: 220904-83-6

GW 5074

Purity: ≥95%

Molecular weight: 520.94g/mol

Ref: 54-BUP10103

GW5074

CAS: 220904-83-6

Formula: C₁₅H₈Br₂INO₂

Molecular weight: 520.94

Ref: 7W-GK6348

3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one

CAS: 220904-83-6

3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one

Formula: C₁₅H₈Br₂INO₂

Purity: 99.37% (Typical Value in Batch COA)

Color and Shape: yellow solid

Molecular weight: 520.94g/mol

Ref: 54-BISN0227

GW-5074 [Optimized for Cell Culture]

CAS: 220904-83-6

Formula: C₁₅H₈Br₂INO₂

Color and Shape: White to Yellow powder to crystal

Molecular weight: 520.95

Ref: 3B-G0649

GW 5074

CAS: 220904-83-6

GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.

Formula: C₁₅H₈Br₂INO₂

Purity: 99.32%

Color and Shape: Solid

Molecular weight: 520.94

Ref: TM-T6525

Raf1 Kinase Inhibitor I

CAS: 220904-83-6

Raf1 Kinase Inhibitor I is a small molecule inhibitor, which is synthetically derived to target the Raf1 kinase enzyme specifically. It operates by intervening in the kinase signaling pathways, particularly inhibiting the activity of Raf1 kinase, which is part of the MAPK/ERK pathway. This effectively impedes the downstream phosphorylation processes that are crucial for cell proliferation and differentiation.

Formula: C₁₅H₈Br₂INO₂

Purity: Min. 95%

Molecular weight: 520.94 g/mol

Ref: 3D-VIA90483