Raf1 Kinase Inhibitor I
CAS: 220904-83-6
Ref. 3D-VIA90483
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire | |
| 100mg | To inquire |
Product Information
- (3Z)-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1,3-dihydro-2H-indol-2-one
- 2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-
- 3-(3,5-Dibromo-4-Hydroxybenzylidene)-5-Iodoindolin-2-One
- 3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
- 3-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one
- Gw-5074
- Gw5074
Raf1 Kinase Inhibitor I is an inhibitor of mitogen-activated protein kinase (MAPK) and it inhibits Raf1 kinase activity. It has been shown to inhibit the production of inflammatory cytokines, such as colony-stimulating factor and chemokines, in bronchial epithelial cells. Raf1 Kinase Inhibitor I is also a potent inhibitor of neutrophil recruitment by blocking the activation of NF-κB. Raf1 Kinase Inhibitor I was shown to have antitumor activity in some cell lines and may be useful for the treatment of cancer or inflammatory diseases.
Chemical properties
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