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CAS 22199-08-2

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Silver sulfadiazine

Description:
Silver sulfadiazine is a topical antimicrobial agent commonly used in the treatment of burns and skin infections. It is a white to off-white crystalline powder that is poorly soluble in water but soluble in organic solvents. The compound is a combination of silver, a metal known for its antibacterial properties, and sulfadiazine, a sulfonamide antibiotic. Silver sulfadiazine works by releasing silver ions, which exert a broad-spectrum antimicrobial effect against both gram-positive and gram-negative bacteria, as well as some fungi. It is particularly effective in preventing infection in burn wounds, promoting healing while minimizing pain. The compound is typically applied as a cream or ointment and is known for its low toxicity, although it can cause local skin reactions in some individuals. Due to its properties, silver sulfadiazine is a valuable tool in wound care, especially in hospital settings. However, it should be used with caution in patients with a known hypersensitivity to sulfonamides.
Formula:C10H9AgN4O2S
InChI:InChI=1/C10H10N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2,(H,12,13,14);/q;+1
InChI key:InChIKey=UEJSSZHHYBHCEL-UHFFFAOYSA-N
SMILES:O=S=1(N=C2[N]([Ag+]O1)=CC=C[N-]2)C3=CC=C(N)C=C3
Synonyms:
  • (4-Amino-N-pyrimidin-2-ylbenzolsulfonamidato-NN,O1)silber
  • (4-amino-N-pirimidin-2-ilbencenosulfonamidato-NN,O1)plata
  • (4-amino-N-pyrimidin-2-ylbenzenesulphonamidato-NN,O1)silver
  • (4-amino-N-pyrimidine-2-ylbenzenesulfonamidato-NN,O1)argent
  • Altreet-Ag
  • Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, silver complex
  • Dermazin
  • Dermazine
  • Flamazine
  • Flammazine
  • See more synonyms
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