CAS 224311-51-7

2-(Di-tert-butylphosphino)biphenyl

Description:

2-(Di-tert-butylphosphino)biphenyl is a chemical compound characterized by its unique structure, which features a biphenyl backbone substituted with a di-tert-butylphosphino group. This compound is notable for its role as a ligand in various catalytic processes, particularly in transition metal catalysis. The presence of the bulky tert-butyl groups enhances steric hindrance, which can influence the reactivity and selectivity of metal complexes formed with this ligand. Additionally, the phosphino group contributes to the electronic properties of the compound, making it a valuable component in organometallic chemistry. The compound is typically stable under ambient conditions but may require careful handling due to the presence of phosphorus, which can be reactive under certain conditions. Its applications extend to fields such as organic synthesis and materials science, where it can facilitate various chemical transformations. Overall, 2-(Di-tert-butylphosphino)biphenyl exemplifies the intersection of sterics and electronics in ligand design for catalysis.

Formula: C₂₀H₂₇P

InChI: InChI=1S/C20H27P/c1-19(2,3)21(20(4,5)6)18-15-11-10-14-17(18)16-12-8-7-9-13-16/h7-15H,1-6H3

InChI key: InChIKey=CNXMDTWQWLGCPE-UHFFFAOYSA-N

SMILES: P(C(C)(C)C)(C(C)(C)C)C1=C(C=CC=C1)C2=CC=CC=C2

Synonyms:

• (2-Biphenylyl)di-tert-butylphosphine
• (Biphenyl-2-yl)bis(tert-butyl)phosphine
• ([1,1′-Biphenyl]-2-yl)di(tert-butyl)phosphine
• 2-(Di-t-butylphosphino)biphenyl
• 2-(Di-tert-butylphosphino)-1,1′-biphenyl
• Biphenyl-2-Yl(Di-Tert-Butyl)Phosphane
• Di(tert-butyl)(1,1′-biphenyl-2-yl)phosphine
• Di(tert-butyl)(2-phenylphenyl)phosphine
• Di-tert-butyl-o-biphenylphosphine
• Dibutylphosphinobiphenyl
• JohnPhos
• Phosphine, [1,1′-biphenyl]-2-ylbis(1,1-dimethylethyl)-
• [1,1′-Biphenyl]-2-ylbis(1,1-dimethylethyl)phosphine

2-(Di-tert-butylphosphino)biphenyl

CAS: 224311-51-7

Formula: C₂₀H₂₇P

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 298.41

Ref: 3B-D3387

2-(Di-tert-Butylphosphino)biphenyl

CAS: 224311-51-7

Formula: C₂₀H₂₇P

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.4021

Ref: IN-DA0032VJ

2-(Di-tert-butylphosphino)biphenyl

Controlled Product

CAS: 224311-51-7

Formula: C₂₀H₂₇P

Color and Shape: Neat

Molecular weight: 298.4

Ref: TR-D493765

2-[Bis(tert-butyl)phosphino]biphenyl

CAS: 224311-51-7

2-[Bis(tert-butyl)phosphino]biphenyl

Formula: C₂₀H₂₇P

Purity: 97%

Color and Shape: White Solid-Powder

Molecular weight: 298.40214

Ref: 54-OR70086

JohnPhos

CAS: 224311-51-7

2-(Di-tert-Butylphosphino)biphenyl

Formula: C₂₀H₂₇P

Purity: 97%

Molecular weight: 298.4

Ref: IN-DG9101

Biphenyl-2-yl-di-tert-butyl-phosphane

CAS: 224311-51-7

Formula: C₂₀H₂₇P

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.41

Ref: 10-F020715

2-(Di-t-butylphosphino))-1,1'-biphenyl, 99% JohnPhos

CAS: 224311-51-7

2-(Di-t-butylphosphino))-1,1'-biphenyl, 99% JohnPhos

Formula: C₂₀H₂₇P

Purity: 99%

Color and Shape: white xtl.

Molecular weight: 298.41

Ref: 08-15-1045

(2-Biphenyl)di-tert-butylphosphine

CAS: 224311-51-7

2-Biphenyl)di-tert-butylphosphine is a synthetic small molecule that binds to receptors in the body, and has been shown to inhibit cancer cell growth. It also prevents kidney fibrosis by inhibiting production of growth factors such as PDGF and IGF. 2-Biphenyl)di-tert-butylphosphine has shown anti-diabetic effects, which may be due to its ability to activate GLP-1R agonists and inhibit pyrimidine synthesis. This drug has been found to have structural similarities with quinoline derivatives and other nitrogen containing compounds, which may provide insight into its binding mechanism. 2-Biphenyl)di-tert-butylphosphine was synthesized in the reaction between triphenyl phosphite and biphenylene, followed by treatment with tert butanol. The X ray crystal structures of this drug bound to human serum albumin show that the carboxy

Formula: C₂₀H₂₇P

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 298.4 g/mol

Ref: 3D-FB44712