CAS 2244992-76-3

CHMFL-PI3KD-317

CAS: 2244992-76-3

CHMFL-PI3KD-317

Purity: ≥95%

Molecular weight: 494.03g/mol

Ref: 54-BUP07019

(S)-2-Amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide

CAS: 2244992-76-3

(S)-2-Amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (LMB) is a molecule that has been shown to have potent activity against lymphocytic leukemia cells. LMB binds to the cell surface and inhibits the function of the T cell receptor, inhibiting the proliferation of T cells. It also inhibits the activation of B cells and prevents them from differentiating into antibody producing cells. LMB is an inhibitor of erythropoiesis and therefore can be used as a treatment for autoimmune diseases such as lupus erythematosus, rheumatoid arthritis, and multiple sclerosis. This drug can also be used in cancer therapy due to its ability to inhibit chronic lymphocytic leukemia by preventing cellular maturation.

Formula: C₂₁H₂₄ClN₅O₃S₂

Purity: Min. 95%

Molecular weight: 494 g/mol

Ref: 3D-UPD99276

CHMFL-PI3KD-317

CAS: 2244992-76-3

CHMFL-PI3KD-317: potent PI3Kδ inhibitor, IC50=6 nM, orally active, >10x selective vs. PI3K isoforms, anti-cancer.

Formula: C₂₁H₂₄ClN₅O₃S₂

Purity: 99.16%

Color and Shape: Solid

Molecular weight: 494.03

Ref: TM-T10804