CAS 2247544-02-9

WS-383

CAS: 2247544-02-9

WS-383 is a selective, potent and reversible DCN1-UBC12 interaction inhibitor(IC50 of 11 nM).

Formula: C₁₈H₂₁Cl₂N₉S₂

Purity: 98.46%

Color and Shape: Solid

Molecular weight: 498.46

Ref: TM-T13349

WS-383

CAS: 2247544-02-9

WS-383

Formula: C₁₈H₂₁Cl₂N₉S₂

Purity: ≥98%

Molecular weight: 498.46

Ref: 54-BUP12587

WS 383 hydrochloride

CAS: 2247544-02-9

Potent inhibitor of the interaction between defective cullin neddylation protein DCN1 and NEDD8-conjugating enzyme UBC12 with IC50 of 11 nM. WS 383 blocks the DCN1-UBC12 interaction in a reversible manner, selectively inhibits Cul3/1 neddylation and induces accumulation of p21, p27, and NRF2 proteins.

Formula: C₁₈H₂₀ClN₉S₂·HCl

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 498.46 g/mol

Ref: 3D-BW170250