CAS 2247604-77-7

Formula: C31H37N3O3S

InChI: InChI=1S/C31H37N3O3S/c1-31(2,3)25-12-10-22(11-13-25)21-33(4)38(36,37)34-18-6-8-24-20-27(15-17-29(24)34)32-26-14-16-28-23(19-26)7-5-9-30(28)35/h10-17,19-20,32H,5-9,18,21H2,1-4H3

InChI key: PBDLRNAZJPQKGT-UHFFFAOYSA-N

SMILES: CC(C)(C)C1=CC=C(C=C1)CN(C)S(=O)(=O)N2CCCC3=C2C=CC(=C3)NC4=CC5=C(C=C4)C(=O)CCC5

RORγt inverse agonist 34

CAS: 2247604-77-7

RORγt inverse agonist 34 (compound 5a) is an inverse agonist for RORγt, exhibiting an IC50 of 0.094 μM for the inhibition of RORγt-LBD. This compound is utilized in psoriasis research.

Formula: C₃₁H₃₇N₃O₃S

Color and Shape: Solid

Molecular weight: 531.709

Ref: TM-T204288