CAS 2247894-32-0

Formula: C21H25N5O3S

InChI: InChI=1S/C21H25N5O3S/c1-3-26(4-2)30(28,29)25-17-7-5-6-15(12-17)16-10-11-18-19(13-16)23-24-20(18)22-21(27)14-8-9-14/h5-7,10-14,25H,3-4,8-9H2,1-2H3,(H2,22,23,24,27)

InChI key: UCBIQZUJJSVQHL-UHFFFAOYSA-N

SMILES: CCN(CC)S(=O)(=O)NC1=CC=CC(=C1)C2=CC3=C(C=C2)C(=NN3)NC(=O)C4CC4

SGC-AAK1-1

CAS: 2247894-32-0

SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.

Formula: C₂₁H₂₅N₅O₃S

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 427.52

Ref: TM-T12885

N-(6-(3-((N,N-Diethylsulfamoyl)Amino)Phenyl)-1H-Indazol-3-Yl)Cyclopropanecarboxamide

CAS: 2247894-32-0

N-(6-(3-((N,N-Diethylsulfamoyl)Amino)Phenyl)-1H-Indazol-3-Yl)Cyclopropanecarboxamide

Formula: C₂₁H₂₅N₅O₃S

Purity: 95%

Molecular weight: 427.52

Ref: 54-OR1024171

SGC-AAK1-1

CAS: 2247894-32-0

SGC-AAK1-1

Formula: C₂₁H₂₅N₅O₃S

Purity: 99.5%

Molecular weight: 427.52

Ref: 54-BUP15631

SGC AAK1 1

CAS: 2247894-32-0

Formula: C₂₁H₂₅N₅O₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 427.5199

Ref: IN-DA01LQCD

SGC AAK1 1

CAS: 2247894-32-0

Dual inhibitor of the adaptor protein 2-associated kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K) with IC50 values of 270 nM and 1 μM, respectively. In a recent study, SGC AAK1 1 stabilised β-catenin, inhibited phosphorylation of the AP2 complex subunit mu protein (AP2M1) and activated Wnt signalling in in vitro experiments._x000D_

Formula: C₂₁H₂₅N₅O₃S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 427.52 g/mol

Ref: 3D-BS168103

SGC-AAK1-1

CAS: 2247894-32-0

Purity: 97%

Molecular weight: 427.17

Ref: 10-F567272

SGC-AAK1-1

CAS: 2247894-32-0

N-(6-(3-((N,N-Diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide

Formula: C₂₁H₂₅N₅O₃S

Purity: 97%

Molecular weight: 427.52

Ref: IN-DG01117755