CAS 22518-27-0
:4-(4-Chlorophenyl)-2-pyrrolidinone
Description:
4-(4-Chlorophenyl)-2-pyrrolidinone, with the CAS number 22518-27-0, is a chemical compound characterized by its pyrrolidinone structure, which features a five-membered lactam ring. This compound contains a chlorophenyl group, indicating the presence of a chlorine atom attached to a phenyl ring, which contributes to its chemical reactivity and potential biological activity. It is typically a white to off-white solid and is soluble in organic solvents, reflecting its moderate polarity. The presence of the pyrrolidinone moiety suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its ability to interact with biological targets. Additionally, the chlorophenyl substituent may enhance its lipophilicity, influencing its pharmacokinetic properties. Safety and handling precautions should be observed, as with many organic compounds, due to potential toxicity or environmental impact. Overall, 4-(4-Chlorophenyl)-2-pyrrolidinone is of interest in various fields, including organic synthesis and drug development.
Formula:C10H10ClNO
InChI:InChI=1S/C10H10ClNO/c11-9-3-1-7(2-4-9)8-5-10(13)12-6-8/h1-4,8H,5-6H2,(H,12,13)
InChI key:InChIKey=OVRPDYOZYMCTAK-UHFFFAOYSA-N
SMILES:O=C1CC(C2=CC=C(Cl)C=C2)CN1
Synonyms:- (±)-Baclofen lactam
- 2-Pyrrolidinone, 4-(4-Chlorophenyl)-
- 2-Pyrrolidinone, 4-(p-chlorophenyl)-
- 4-(4-Chlorophenyl)-2-pyrrolidone
- 4-(4-Chlorophenyl)pyrrolidin-2-one
- 4-(4-Chlorophenyl)-2-pyrrolidinone
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Found 11 products.
Baclofen Related Compound A (4-(4-Chlorophenyl)-2-pyrrolidinone)
CAS:Lactams, nesoiFormula:C10H10ClNOColor and Shape:White CrystalsMolecular weight:195.045094-(4-Chlorophenyl)pyrrolidin-2-one
CAS:Formula:C10H10ClNOPurity:97%Color and Shape:SolidMolecular weight:195.64554-(4-Chlorophenyl)pyrrolidin-2-one
CAS:4-(4-Chlorophenyl)pyrrolidin-2-oneFormula:C10H10ClNOPurity:98%Molecular weight:195.65Baclofen EP Impurity A (Baclofen USP Related Compound A)
CAS:Formula:C10H10ClNOColor and Shape:White To Off-White SolidMolecular weight:195.65Baclofen EP Impurity A
CAS:Controlled ProductFormula:C10H10ClNOColor and Shape:NeatMolecular weight:195.654-(4-Chlorophenyl)-2-pyrrolidinone
CAS:Controlled ProductImpurity Baclofen EP Impurity A
Applications 4-(4-Chlorophenyl)-2-pyrrolidinone is used in the preparation of potential and selective antagonists of the α1A adrenergic receptor (1,2). It is an impurity of Baclofen (B108000), a specific GABA-B receptor agonist. Muscle relaxant (skeletal).
References (1) Whitlock, G. et al.: Bioorg. med. Chem. Lett., 19, 3118 (2009)(2) Brogden, R.N., et al.: Drugs, 8,1 (1974)Formula:C10H10ClNOColor and Shape:NeatMolecular weight:195.654-(4-Chlorophenyl)-2-pyrrolidinone
CAS:4-(4-Chlorophenyl)-2-pyrrolidinone (4CPP) is an anti-convulsant drug that is used to treat epilepsy. It has a high boiling point, allowing it to be used in liquid chromatography methods. 4CPP is also used as a solvent for drugs and excipients in the pharmaceutical industry, and can be obtained through chemical synthesis or by dehydration of butyric acid. The reaction products are trehalose, which is a sugar that prevents the formation of ice crystals, and gabapentin, which is an anti-convulsant drug. 4CPP can be synthesized on an on-line basis using electrospray ionization with a liquid chromatograph/mass spectrometer system. It has been shown to have clinical use in the treatment of epilepsy.Formula:C10H10ClNOPurity:Min. 95%Molecular weight:195.65 g/mol4-(4-CHLOROPHENYL)PYRROLIDIN-2-ONE
CAS:Formula:C10H10ClNOPurity:98%Color and Shape:SolidMolecular weight:195.65
