
CAS 2254492-08-3
:Formula:C27H27N5O7S2
InChI:InChI=1S/C27H27N5O7S2/c1-39-19-8-12-21(13-9-19)41(37,38)32(17-27(30)34)25-15-14-24(22-4-2-3-5-23(22)25)31(16-26(29)33)40(35,36)20-10-6-18(28)7-11-20/h2-15H,16-17,28H2,1H3,(H2,29,33)(H2,30,34)
InChI key:DFIZGWXPFCOCFG-UHFFFAOYSA-N
SMILES:COC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)N)C2=CC=C(C3=CC=CC=C32)N(CC(=O)N)S(=O)(=O)C4=CC=C(C=C4)N
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2-((N-(4-((4-Amino-N-(2-amino-2-oxoethyl)phenyl)sulfonamido)naphthalen-1-yl)-4-methoxyphenyl)sulfonamido)acetamide
CAS:2-((N-(4-((4-Amino-N-(2-amino-2-oxoethyl)phenyl)sulfonamido)naphthalen-1-yl)-4-methoxyphenyl)sulfonamido)acetamideFormula:C27H27N5O7S2Purity:99%Molecular weight:597.68NXPZ-2
CAS:2-((N-(4-((4-Amino-N-(2-amino-2-oxoethyl)phenyl)sulfonamido)naphthalen-1-yl)-4-methoxyphenyl)sulfonamido)acetamideFormula:C27H27N5O7S2Purity:99%Molecular weight:597.66NXPZ-2
CAS:NXPZ-2 is an orally active Keap1-Nrf2 PPI inhibitor (Kᵢ = 95 nM, EC₅₀ = 120–170 nM) that upregulates Nrf2 and alleviates Aβ-induced cognitive impairment.Formula:C27H27N5O7S2Color and Shape:SolidMolecular weight:597.66



