CAS 2254608-80-3

1,1-Cyclopropanedicarboxamide, N-[4-[[7-[3-[3-[3-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]ethyl]amino]-3-oxopropoxy]propoxy]propoxy]-6-methoxy-4-quinolinyl]oxy]-3-fluorophenyl]-N'-(4-fluorophenyl)-

Formula: C₅₁H₅₀F₂N₆O₁₃

InChI: InChI=1S/C51H50F2N6O13/c1-67-41-28-34-36(54-19-15-38(34)72-39-13-11-32(27-35(39)53)57-50(66)51(17-18-51)49(65)56-31-9-7-30(52)8-10-31)29-42(41)70-24-4-23-68-21-3-22-69-25-16-43(60)55-20-26-71-40-6-2-5-33-45(40)48(64)59(47(33)63)37-12-14-44(61)58-46(37)62/h2,5-11,13,15,19,27-29,37H,3-4,12,14,16-18,20-26H2,1H3,(H,55,60)(H,56,65)(H,57,66)(H,58,61,62)

InChI key: ZAJXSUNUSHEGCB-UHFFFAOYSA-N

SMILES: COC1=CC2=C(C=CN=C2C=C1OCCCOCCCOCCC(=O)NCCOC3=CC=CC4=C3C(=O)N(C4=O)C5CCC(=O)NC5=O)OC6=C(C=C(C=C6)NC(=O)C7(CC7)C(=O)NC8=CC=C(C=C8)F)F

Synonyms:

• 1,1-Cyclopropanedicarboxamide, N-[4-[[7-[3-[3-[3-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]ethyl]amino]-3-oxopropoxy]propoxy]propoxy]-6-methoxy-4-quinolinyl]oxy]-3-fluorophenyl]-N'-(4-fluorophenyl)-

PROTAC c-Met degrader-2

CAS: 2254608-80-3

PROTACc-Met degrader-2 (PROTAC2) is a c-Met degrader developed using PROTAC technology, with a DC50 value of 50 nM.

Formula: C₅₁H₅₀F₂N₆O₁₃

Color and Shape: Solid

Molecular weight: 992.97

Ref: TM-T203391