CAS 22560-50-5: Clodronate sodium
Description:Clodronate sodium is a bisphosphonate compound primarily used in the treatment of bone disorders, particularly in conditions such as osteoporosis and metastatic bone disease. It functions by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain bone density and strength. The chemical formula for clodronate sodium is C5H6Cl2NaO3P, and it is characterized by its ability to bind to hydroxyapatite in bone tissue. This compound is typically administered orally or intravenously, depending on the clinical indication. Clodronate sodium is known for its relatively low toxicity profile compared to other bisphosphonates, making it a preferred choice in certain therapeutic contexts. It is also utilized in research settings to study bone metabolism and the effects of bisphosphonates on various biological processes. As with any medication, potential side effects may include gastrointestinal disturbances and, in rare cases, osteonecrosis of the jaw, necessitating careful monitoring during treatment.
Formula:CH4Cl2O6P2·2Na
InChI:InChI=1S/CH4Cl2O6P2.2Na/c2-1(3,10(4,5)6)11(7,8)9;;/h(H2,4,5,6)(H2,7,8,9);;
InChI key:InChIKey=OQNIOBHHYSEHCE-UHFFFAOYSA-N
SMILES:[Na].O=P(O)(O)C(Cl)(Cl)P(=O)(O)O
- Synonyms:
- (Dichloromethylene)diphosphonate disodium
- Bm 06011
- Bonefos
- Clasteon
- Clodronate
- Clodronate disodium
- Clodronate disodium salt
- Clodronate sodium
- Clodronic Acid Disodium Salt
- DClMDP
- See more synonyms
- Dichloromethylenebisphosphonic acid disodium salt
- Dichloromethylenediphosphonic Acid Disodium Salt
- Difoafonal
- Diphosfonal
- Disodium (Dichloromethanediyl)Bis[Hydrogen (Phosphonate)]
- Disodium (dichloromethane)diphosphonate
- Disodium (dichloromethylene)bisphosphonate
- Disodium (dichloromethylene)diphosphonate
- Disodium clodronate
- Disodium dichloromethylenebis(hydrogenphosphonate) tetrahydrate
- Lodronate
- Loron
- Mebonat
- Ossiten
- Ostac
- Phosphonic acid, (dichloromethylene)bis-, disodium salt
- Phosphonic acid, (dichloromethylene)di-, disodium salt
- Phosphonic acid, P,P′-(dichloromethylene)bis-, sodium salt (1:2)
- Sodium (dichloromethylene)diphosphonate
- Sodium clodronate
