CAS 2270-40-8

Diacetoxyscirpenol

Description:

Diacetoxyscirpenol, also known as DAS, is a mycotoxin produced by certain species of fungi, particularly those in the Fusarium genus. It is characterized by its chemical structure, which includes two acetoxy groups attached to a scirpenol backbone. This compound is known for its toxicological effects, particularly in agricultural contexts, as it can contaminate crops and pose risks to livestock and human health. Diacetoxyscirpenol exhibits immunosuppressive properties and can affect the gastrointestinal tract, leading to symptoms such as vomiting and diarrhea in animals. Its presence in food products is regulated due to its potential health hazards. The compound is typically analyzed using advanced techniques such as chromatography and mass spectrometry to ensure food safety and compliance with regulatory standards. Additionally, research continues to explore its mechanisms of action and the broader implications of mycotoxin contamination in food systems. Overall, diacetoxyscirpenol is a significant concern in food safety and agricultural practices due to its toxic nature and potential health impacts.

Formula: C₁₉H₂₆O₇

InChI: InChI=1S/C19H26O7/c1-10-5-6-18(8-23-11(2)20)13(7-10)26-16-14(22)15(25-12(3)21)17(18,4)19(16)9-24-19/h7,13-16,22H,5-6,8-9H2,1-4H3/t13-,14-,15-,16-,17-,18-,19+/m1/s1

InChI key: InChIKey=AUGQEEXBDZWUJY-NMAPUUFXSA-N

SMILES: C[C@@]12[C@@]3([C@@]([C@H](O)[C@H]1OC(C)=O)(O[C@]4([C@]2(COC(C)=O)CCC(C)=C4)[H])[H])CO3

Synonyms:

• (3Alpha,4Beta)-3-Hydroxy-12,13-Epoxytrichothec-9-Ene-4,15-Diyl Diacetate
• (3Beta,4Alpha,12Xi)-3-Hydroxy-12,13-Epoxytrichothec-9-Ene-4,15-Diyl Diacetate
• (3beta,4alpha,12R)-3-hydroxy-12,13-epoxytrichothec-9-ene-4,15-diyl diacetate
• 2,2'-(E)-ethene-1,2-diylbis(5-aminobenzenesulfonic acid)
• 3-Hydroxy-12,13-Epoxytrichothec-9-Ene-4,15-Diyl Diacetate
• 4,15-Di-O-acetylscirpenol
• 4,15-Diacetoxyscirp-9-en-3-ol
• 4,15-Diacetoxyscirpen-3-ol
• 4,15-Diacetoxyscirpenol
• 4beta,15-Diacetoxy-3alpha-hydroxy-12,13-epoxytrichothec-9-ene
• 4β,15-Diacetoxy-12,13-epoxytrichothec-9-en-3α-ol
• Ang 66
• Anguidin
• Anguidine
• Mm 4462
• NSC 141537
• NSC 177378
• Scirp-9-ene-3α,4β,15-triol, 4,15-diacetate
• Scirpenetriol 4,15-diacetate
• Spiro(2,5-methano-1-benzoxepin-10,2'-oxirane)-5a(6H)-methanol, 2,3,4,5,7,9a-hexahydro-3,4-dihydroxy-5,8-dimethyl-, 4,5a-diacetate
• Trichothec-9-ene, 12,13-epoxy-4beta,15-diacetoxy-3alpha-hydroxy-
• Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 4,15-diacetate
• Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 4,15-diacetate, (3alpha,4beta)-
• Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 4,15-diacetate, (3α,4β)-
• Trichothec-9-ene-3alpha,4beta,15-triol, 12,13-epoxy-, 4,15-diacetate
• Trichothec-9-ene-3α,4β,15-triol, 12,13-epoxy-, 4,15-diacetate

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Controlled Product

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8, 5975-78-0

Color and Shape: Mixture

Ref: 04-V30000004AL

Diacetoxyscirpenol 100 µg/mL in Acetonitrile

Controlled Product

CAS: 2270-40-8

Formula: C₁₉H₂₆O₇

Color and Shape: Single Solution

Molecular weight: 366.41

Ref: 04-A12174000AL-100

Diacetoxyscirpenol 13C19 25 µg/mL in Acetonitrile

Controlled Product

CAS: 2270-40-8

Formula: C₁₉H₂₆O₇

Color and Shape: Single Solution

Molecular weight: 385.266

Ref: 04-A12174010AL-25

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Controlled Product

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8

Color and Shape: Mixture

Ref: 04-A30000004AL

Diacetoxyscirpenol Standard Solution

CAS: 2270-40-8

Diacetoxyscirpenol Standard Solution

Formula: C₁₉H₂₆O₇

Purity: By hplc: 100% (Typical Value in Batch COA)

Color and Shape: clear. colourless liquid

Molecular weight: 366.41g/mol

Ref: 54-BIMS125

Diacetoxyscirpenol

CAS: 2270-40-8

Formula: C₁₉H₂₆O₇

Molecular weight: 366.41

Ref: 4Z-S-164002

Diacetoxyscirpenol

Controlled Product

CAS: 2270-40-8

Diacetoxyscirpenol is a mycotoxin that is found in wastewater and has been shown to have the ability to inhibit certain enzyme activities. It is a glucuronide conjugate that is excreted by humans, and can be detected in urine samples. The metabolite of Diacetoxyscirpenol, 4-hydroxy-2,3-dihydroxymethyl-5-(2H)-furanone (4OH-DMF), has been shown to induce antibody response in mice. The LC-MS/MS method for detecting Diacetoxyscirpenol uses a monoclonal antibody that recognizes the toxin. This antibody binds to the toxin and activates an enzyme cascade that leads to the production of a fluorescent dye. The intensity of fluorescence can be quantified using fluorometry or spectrophotometry. /nowiki>/pre>

Formula: C₁₉H₂₆O₇

Purity: Min. 95%

Molecular weight: 366.41 g/mol

Ref: 3D-FD63584

Diacetoxyscirpenol

CAS: 2270-40-8

Diacetoxyscirpenol: a fungal mycotoxin causing blood disorders in humans/animals.

Formula: C₁₉H₂₆O₇

Purity: 98%

Color and Shape: Solid Solid

Molecular weight: 366.41

Ref: TM-T15111

Diacetoxyscirpenol 100 µg/mL in Acetonitrile

Controlled Product

CAS: 2270-40-8

Formula: C₁₉H₂₆O₇

Color and Shape: Single Solution

Molecular weight: 366.41

Ref: 04-V12174000AL-100

Diacetoxyscirpenol

CAS: 2270-40-8

Diacetoxyscirpenol

Formula: C₁₉H₂₆O₇

Purity: By hplc: 98.36% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 366.41g/mol

Ref: 54-BID1003

Diacetoxyscirpenol

Controlled Product

CAS: 2270-40-8

Applications Diacetoxyscirpenolis is a trichothecene mycotoxin produced by various Fusarium strains. Diacetoxyscirpenol was found to occur in cereals conjugated to glucose and other sugars.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rasmussen, P.H., et al.: Mycotoxin, Res., 28, 181 (2012); Scauflaire, J., et al.: Euro. J. Pathol., 133, 911 (2012); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Formula: C₁₉H₂₆O₇

Color and Shape: Neat

Molecular weight: 366.41

Ref: TR-D307550