CAS 2273-93-0

2,6-Dichloro-7-methyl-7H-purine

Description:

2,6-Dichloro-7-methyl-7H-purine, with the CAS number 2273-93-0, is a purine derivative characterized by the presence of two chlorine atoms at the 2 and 6 positions and a methyl group at the 7 position of the purine ring. This compound is typically a white to off-white solid and is soluble in polar organic solvents. It exhibits properties typical of purines, including potential biological activity, as purines are fundamental components of nucleic acids. The presence of chlorine substituents can influence its reactivity and interaction with biological systems, potentially affecting its role in biochemical pathways. 2,6-Dichloro-7-methyl-7H-purine may be utilized in research settings, particularly in studies related to nucleic acid chemistry or as a precursor in the synthesis of other bioactive compounds. Safety data should be consulted for handling and storage, as halogenated compounds can pose health risks.

Formula: C₆H₄Cl₂N₄

InChI: InChI=1S/C6H4Cl2N4/c1-12-2-9-5-3(12)4(7)10-6(8)11-5/h2H,1H3

InChI key: InChIKey=HVMUWHZAZGTMJK-UHFFFAOYSA-N

SMILES: ClC1=C2C(=NC(Cl)=N1)N=CN2C

Synonyms:

• 2,6-Dichloro-7-methyl-7H-purine
• 5,7-Dichloro-1-methyl-1H-imidazo[4,5-d]pyrimidine
• 7H-Purine, 2,6-dichloro-7-methyl-
• NSC 7853
• Purine, 2,6-dichloro-7-methyl-
• 2,6-Dichloro-7-methylpurine

2,6-DICHLORO-7-METHYLPURINE

CAS: 2273-93-0

Formula: C₆H₄Cl₂N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 203.0288

Ref: IN-DA003G35

2,6-Dichloro-7-methylpurine

CAS: 2273-93-0

Ref: 7W-GN8957

2,6-Dichloro-7-methylpurine

CAS: 2273-93-0

2,6-Dichloro-7-methylpurine

Purity: 99%

Molecular weight: 203.03g/mol

Ref: 54-OR90624

2,6-Dichloro-7-methylpurine

CAS: 2273-93-0

Formula: C₆H₄Cl₂N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 203.03

Ref: 10-F317843

2,6-Dichloro-7-methylpurine

CAS: 2273-93-0

2,6-Dichloro-7-methylpurine (2,6-DCMP) is a chlorinated purine analog that has anticancer activity. It is an ATP competitive inhibitor that inhibits protein synthesis by competitively binding to the alpha subunit of the ribosome. 2,6-DCMP has been shown to have strong antiviral activity against human immunodeficiency virus and cytotoxic effects on human adenocarcinoma cells in vitro. The IC50 values for this compound are 50 nM against HIV and 5 μM against human adenocarcinoma cells.

Formula: C₆H₄Cl₂N₄

Purity: Min. 95%

Molecular weight: 203.03 g/mol

Ref: 3D-ND29030