CAS 2276-94-0
:(3α,5α)-3-Hydroxycholan-24-oic acid
Description:
(3α,5α)-3-Hydroxycholan-24-oic acid, commonly known as chenodeoxycholic acid, is a bile acid that plays a crucial role in the digestion and absorption of dietary fats. It is a steroid acid derived from cholesterol and is characterized by its hydroxyl groups at the 3α and 5α positions, which contribute to its amphipathic nature, allowing it to interact with both lipids and water. This compound is typically found in the bile of mammals and is involved in the emulsification of fats, facilitating their breakdown by digestive enzymes. Chenodeoxycholic acid also has therapeutic applications, particularly in the treatment of certain types of gallstones and as a cholesterol-lowering agent. Its molecular structure includes a steroid backbone with a carboxylic acid functional group, which enhances its solubility in bile. Additionally, it is important in the regulation of cholesterol metabolism and has been studied for its potential effects on liver function and lipid profiles. Overall, (3α,5α)-3-Hydroxycholan-24-oic acid is a significant biochemical compound with various physiological and pharmacological implications.
Formula:C24H40O3
InChI:InChI=1/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16+,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChI key:InChIKey=SMEROWZSTRWXGI-NWFSOSCSSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Synonyms:- (3α,5α)-3-Hydroxycholan-24-oic acid
- 2276-94-0
- 3α-Hydroxy-5α-cholanoic acid
- 5α-Cholan-24-oic acid, 3α-hydroxy-
- 5α-Cholanic acid, 3α-hydroxy-
- Allolithocholic acid
- Cholan-24-oic acid, 3-hydroxy-, (3α,5α)-
- 5α-CHOLANIC ACID-3α-OL
- (4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
- Allocholic Acid Impurity 2
- Allolithocholic acid (ALCA)
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Allolithocholic acid
CAS:Allolithocholic acid (allo-LCA) is found in the urine of infants with biliary atresia and promotes intestinal and hepatic metabolism.Formula:C24H40O3Purity:98.00% - 98.00%Color and Shape:White SolidMolecular weight:376.57Allolithocholic acid
CAS:Controlled ProductApplications Allolithocholic acid is used as steroid compound as T regulatory lymphocyte modulators and uses for treatment of inflammatory or autoimmune disorders.
References Littman, D. R., et al.: PCT Int. Appl. 160pp. (2020)Formula:C24H40O3Color and Shape:NeatMolecular weight:376.58Allolithocholic acid
CAS:Controlled ProductAllolithocholic acid is a secondary bile acid, which is derived from the microbial metabolism of primary bile acids within the intestinal tract. Its mode of action involves interactions with nuclear receptors and membrane-bound receptors that regulate various metabolic pathways, including lipid metabolism and glucose homeostasis. These interactions suggest its potential to influence cholesterol levels and glycemic control.Formula:C24H40O3Purity:Min. 95%Color and Shape:PowderMolecular weight:376.6 g/molAllolithocholic acid (Standard)
CAS:Allolithocholic acid (Standard) is a reference standard for research and analysis in studies involving Allolithocholic acid. Allolithocholic acid (allo-LCA) is found in the urine of infants with biliary atresia and is often excreted as sulfate-conjugated bile acids.Allolithocholic acid promotes intestinal and hepatic metabolism.Formula:C24H40O3Molecular weight:376.57
