CAS 22818-40-2
:D-p-Hydroxyphenylglycine
Description:
D-p-Hydroxyphenylglycine, with the CAS number 22818-40-2, is an amino acid derivative characterized by its phenolic and glycine components. It features a hydroxyl group (-OH) attached to the para position of the phenyl ring, which contributes to its solubility and reactivity. This compound is often studied for its potential applications in pharmaceuticals, particularly as a building block in the synthesis of various biologically active molecules. D-p-Hydroxyphenylglycine exhibits chirality, with specific stereochemical configurations influencing its biological activity. It is typically a white to off-white crystalline solid, soluble in water and organic solvents, making it versatile for various chemical reactions. The presence of both amino and carboxyl functional groups allows it to participate in typical amino acid reactions, such as peptide bond formation. Additionally, its structural features may enable interactions with biological receptors, making it of interest in medicinal chemistry and drug design. Overall, D-p-Hydroxyphenylglycine is a significant compound in both synthetic and biological chemistry contexts.
Formula:C8H9NO3
InChI:InChI=1S/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m1/s1
InChI key:InChIKey=LJCWONGJFPCTTL-SSDOTTSWSA-N
SMILES:[C@@H](C(O)=O)(N)C1=CC=C(O)C=C1
Synonyms:- (2R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
- (2R)-2-Azaniumyl-2-(4-hydroxyphenyl)acetate
- (2R)-2-amino-2-phenylethanamide
- (2R)-amino(4-hydroxyphenyl)ethanoic acid
- (R)-(-)-alpha-Amino-(4-hydroxyphenyl)acetic acid
- (R)-(4-Hydroxyphenyl)glycine
- (R)-2-(4-Hydroxyphenyl)glycine
- (R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
- (αR)-α-Amino-4-hydroxybenzeneacetic acid
- 2-(4-Hydroxy-phenyl)glycin D-Form
- 4-Hydroxy-<span class="text-smallcaps">D</span>-phenylglycine
- 4-Hydroxy-D-Phenylglycine
- <span class="text-smallcaps">D</span>-(-)-2-(4-Hydroxyphenyl)glycine
- <span class="text-smallcaps">D</span>-(-)-2-(p-Hydroxyphenyl)glycine
- <span class="text-smallcaps">D</span>-(-)-4-Hydroxyphenylglycine
- <span class="text-smallcaps">D</span>-(-)-Amino(4-hydroxyphenyl)acetic acid
- <span class="text-smallcaps">D</span>-(-)-p-Hydroxyphenylglycine
- <span class="text-smallcaps">D</span>-(-)-α-(4-Hydroxyphenyl)glycine
- <span class="text-smallcaps">D</span>-(-)-α-Amino-4-hydroxyphenylacetic acid
- <span class="text-smallcaps">D</span>-(-)-α-Amino-p-hydroxyphenylacetic acid
- <span class="text-smallcaps">D</span>-2-Amino-2-(p-hydroxyphenyl)acetic acid
- <span class="text-smallcaps">D</span>-α-p-Hydroxyphenylglycine
- Benzeneacetic acid, α-amino-4-hydroxy-, (R)-
- Benzeneacetic acid, α-amino-4-hydroxy-, (αR)-
- D(-)-Alpha-Parahydroxy Phenylglycine
- D(-)4-P-hydroxyphenylglycine
- D-(-)-2-(4-Hydroxyphenyl)Glycine
- D-p-hydroxyphenylglycine
- Glycine, 2-(p-hydroxyphenyl)-, <span class="text-smallcaps">D</span>-
- H-D-Phg(4-OH)-OH
- PH Dane-acid
- p-Hydroxy-(R)-phenylglycine
- p-Hydroxy-<span class="text-smallcaps">D</span>-phenylglycine
- See more synonyms
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4-Hydroxy-D-(-)-2-phenylglycine
CAS:Formula:C8H9NO3Purity:>99.0%(HPLC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:167.16(-)-4-Hydroxy-D-phenylglycine, 98+%
CAS:(-)-4-Hydroxy-D-phenylglycine is used as an organic chemical synthesis intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / itemFormula:C8H9NO3Purity:98+%Color and Shape:White to pale cream, Crystals or powder or crystalline powderMolecular weight:167.16Amoxicillin Related Compound I ((R)-2-Amino-2-(4-hydroxyphenyl)acetic acid)
CAS:Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C8H9NO3Color and Shape:White Crystalline PowderMolecular weight:167.05824(R)-2-(4-Hydroxyphenyl)glycine
CAS:Formula:C8H9NO3Purity:96%Color and Shape:SolidMolecular weight:167.1620Amoxicillin EP Impurity I (Amoxicillin USP Related Compound I, Cefadroxil EP Impurity A)
CAS:Formula:C8H9NO3Color and Shape:White To Off-White SolidMolecular weight:167.164-Hydroxy-D-phenylglycine
CAS:4-Hydroxy-D-phenylglycineFormula:C8H9NO3Purity:98%Color and Shape:Solid-CrystalsMolecular weight:167.161964-Hydroxy-D-phenylglycine
CAS:Formula:C8H9NO3Purity:≥ 99.0%Color and Shape:White to off-white crystalline powderMolecular weight:167.16D-α-(4-Hydroxyphenyl-2,3,56-d4)glycine-α-d1
CAS:Formula:HOC6D4CD(NH2)COOHPurity:98 atom % DMolecular weight:172.08963Amoxicillin EP Impurity I (Cefadroxil EP Impurity A)
CAS:Controlled ProductFormula:C8H9NO3Color and Shape:NeatMolecular weight:167.16D-4-Hydroxyphenylglycine
CAS:D-4-Hydroxyphenylglycine is key in making β-lactam antibiotics like Amoxicillin and Cefadroxil.Formula:C8H9NO3Color and Shape:SolidMolecular weight:167.164-Hydroxy-D-(-)-2-phenylglycine
CAS:Controlled ProductImpurity Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)
Applications 4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)) is an compound used mainly for the synthetic preparation of β-lactam antibiotics.
References Koide, H., et al.: J. Antibio., 65, 91 (2012); Aranaz, I., et al.: Enzyme. Micro. Tech., 39, 215 (2006);Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.16(R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
CAS:Formula:C8H9NO3Purity:98%Color and Shape:SolidMolecular weight:167.164(R)-2-Amino-2-(4-hydroxyphenyl)acetic acid, Amoxicillin Impurity
CAS:Purity:98%Molecular weight:167.06D-Alpha-(4-Hydroxyphenyl-2,3,5,6-d4)glycine-Alpha-d1
CAS:Controlled ProductFormula:C8D5H4NO3Color and Shape:NeatMolecular weight:172.19















