CAS 22832-87-7
:Miconazole nitrate
Description:
Miconazole nitrate is an antifungal agent commonly used in the treatment of various fungal infections, particularly those affecting the skin and mucous membranes. It belongs to the imidazole class of antifungals and works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Miconazole nitrate is typically available in various formulations, including creams, powders, and vaginal suppositories, making it versatile for different applications. The substance is characterized by its white to off-white crystalline powder form, with a relatively low solubility in water but better solubility in organic solvents. It is generally well-tolerated, though some individuals may experience local irritation or allergic reactions. Miconazole nitrate is also notable for its broad-spectrum activity against a range of fungi, including dermatophytes and yeasts, making it effective for conditions such as athlete's foot, ringworm, and candidiasis. Its mechanism of action and efficacy have made it a staple in both over-the-counter and prescription antifungal therapies.
Formula:C18H14Cl4N2O·HNO3
InChI:InChI=1S/C18H14Cl4N2O.HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)
InChI key:InChIKey=MCCACAIVAXEFAL-UHFFFAOYSA-N
SMILES:C(CN1C=CN=C1)(OCC2=C(Cl)C=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3.N(=O)(=O)O
Synonyms:- 1-(2,4-Dichloro-Beta-[(2,4-Dichlorobenzyl)Oxy]Phenethyl)Imidazole Nitrate
- 1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
- 1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1)
- 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, mononitrate
- 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, nitrate (1:1)
- Aflorix
- Albistat
- Andergin
- Antifungal Cream
- Brentan
- Conoderm
- Conofite
- Dactrine
- Daktar
- Daktarin
- Daktarin talc
- Deralbine
- Dermonistat
- Ecobi
- Epi-Monistat
- Florid
- Fungiderm
- Fungisdin
- Gyno-Daktarin
- Gyno-Monistat
- Hi-Pick
- Imidazole, 1-[2,4-dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl]-, mononitrate
- Loptrimin AF Jock-Itch Powder Aerosol
- Lotrimin AF Powder
- Lotrimin AF Powder Aerosol
- Lotrimin AF Spray Liquid
- Micatin
- Miconal
- Miconaz
- Miconazole Nitrite
- Micotef
- Monistat
- Monistat Cream and Suppositories
- Monistat-Derm
- NSC 169434
- Plus-Minus-Miconazole Nitrate*Crystalline
- Priconazole
- Prilagin
- R 14889
- Vodol
- Zeasorb AF
- Zimycan
- [2,4-Dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazole nitrate
- (+/-)-MICONAZOLE NITRATE
- See more synonyms
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Miconazole Nitrate
CAS:Formula:C18H14Cl4N2O·HNO3Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:479.14(+/-)-Miconazole nitrate, 98+%
CAS:<p>Inhibits cytochrome P450-dependent 14a-demethylase</p>Formula:C18H14Cl4N2O•HNO3Purity:98+%Molecular weight:479.15Miconazole nitrate
CAS:Miconazole nitrateFormula:C18H14C14N2O / C18H14C14N2OHNO3Purity:86.4% / 99.5%Color and Shape:WhiteMolecular weight:442.11061MICONAZOLE NITRATE CRS
CAS:<p>MICONAZOLE NITRATE CRS</p>Formula:C18H15Cl4N3O4Color and Shape:White. Powder.Molecular weight:479.1414Miconazole Nitrate
CAS:<p>Compounds containing an unfused imidazole ring (whether</p>Formula:C18H14Cl4N2O·HNO3Color and Shape:White Off-White PowderMolecular weight:476.98167Miconazole nitrate
CAS:<p>Miconazole nitrate, an antifungal, targets fungal cell membranes rich in ergosterol, distinct from mammalian cells.</p>Formula:C18H15Cl4N3O4Purity:99.51%Color and Shape:White Crystal PowderMolecular weight:479.15Isoconazole Nitrate EP Impurity C Nitrate (Isoconazole EP Impurity D Nitrate, Miconazole Nitrate)
CAS:Formula:C18H14Cl4N2O·HNO3Color and Shape:White To Off-White SolidMolecular weight:416.14 63.01Miconazole nitrate salt, EP grade
CAS:Formula:C18H14Cl4N2OHNO3Purity:99.0 - 101.0 % (dried substance)Color and Shape:White or almost white powderMolecular weight:479.15Miconazole nitrate salt
CAS:Formula:C18H14Cl4N2OHNO3Purity:(Titration) ≥ 98.0%Color and Shape:White or almost white powder or crystalsMolecular weight:479.15Miconazole nitrate
CAS:<p>Miconazole nitrate</p>Purity:98%Color and Shape:SolidMolecular weight:479.14g/mol(±)-Miconazole-d5 Nitrate(2,4-dichlorobenzyloxy-d5)
CAS:Purity:98 atom % DColor and Shape:White To Off White SolidMolecular weight:484.14Miconazole Nitrate
CAS:Controlled ProductFormula:C18H14Cl4N2O·HNO3Color and Shape:NeatMolecular weight:479.14Miconazole Nitrate
CAS:Controlled Product<p>Applications Antifungal (topical).<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H14Cl4N2O·HNO3Color and Shape:NeatMolecular weight:479.14Miconazole nitrate - Bio-X ™
CAS:<p>Miconazole is an antifungal drug that is used for the treatment of fungal infections. This drug has broad-spectrum activity and works by inhibiting fungal CYP450 14α-lanosterol demethylase activity. This leads to altered ergosterol production and an impaired cell membrane.</p>Formula:C18H14Cl4N2O•HNO3Purity:Min. 95%Color and Shape:PowderMolecular weight:479.14 g/molMiconazole nitrate
CAS:<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>Formula:C18H14Cl4N2O•HNO3Purity:Min. 95%Color and Shape:PowderMolecular weight:479.14 g/molMiconazole Nitrate (MCN)extrapure, 98%
CAS:Formula:C18H14Cl2N2O·HNO3Purity:min. 98%Color and Shape:White to off-white, PowderMolecular weight:479.14
