CAS 22978-25-2

2-Chloro-5-nitrobenzanilide

Description:

2-Chloro-5-nitrobenzanilide, with the CAS number 22978-25-2, is an organic compound characterized by its aromatic structure, which includes a chloro group and a nitro group attached to a benzanilide framework. This compound typically appears as a solid and is known for its moderate solubility in organic solvents. The presence of the chloro and nitro substituents contributes to its chemical reactivity, making it useful in various synthetic applications, particularly in the field of pharmaceuticals and agrochemicals. Its molecular structure allows for potential interactions in biological systems, which may lead to specific pharmacological effects. Additionally, 2-Chloro-5-nitrobenzanilide may exhibit properties such as antimicrobial or herbicidal activity, depending on its application. Safety data sheets should be consulted for handling and toxicity information, as compounds with halogen and nitro groups can pose health risks. Overall, this compound serves as an important intermediate in organic synthesis and research.

Formula: C₁₃H₉ClN₂O₃

InChI: InChI=1S/C13H9ClN2O3/c14-12-7-6-10(16(18)19)8-11(12)13(17)15-9-4-2-1-3-5-9/h1-8H,(H,15,17)

InChI key: InChIKey=DNTSIBUQMRRYIU-UHFFFAOYSA-N

SMILES: C(NC1=CC=CC=C1)(=O)C2=CC(N(=O)=O)=CC=C2Cl

Synonyms:

• 2-Chloro-5-nitrobenzanilide
• Benzamide, 2-chloro-5-nitro-N-phenyl-
• Benzanilide, 2-chloro-5-nitro-
• Gw 9622
• Gw 9662
• Gw9662
• 2-Chloro-5-nitro-N-phenylbenzamide

GW 9662

CAS: 22978-25-2

Formula: C₁₃H₉ClN₂O₃

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 276.68

Ref: 3B-C4016

GW 9662

CAS: 22978-25-2

An irreversible PPAR antagonist

Formula: C₁₃H₉ClN₂O₃

Color and Shape: Solid, White to off-white

Molecular weight: 276.68

Ref: 02-J65634

GW9662

CAS: 22978-25-2

GW9662

Formula: C₁₃H₉ClN₂O₃

Purity: ≥98%

Molecular weight: 276.68

Ref: 54-BUP10520

GW9662

CAS: 22978-25-2

Formula: C₁₃H₉ClN₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 276.6752

Ref: IN-DA002LRE

2-Chloro-5-Nitro-N-Phenylbenzamide

CAS: 22978-25-2

2-Chloro-5-Nitro-N-Phenylbenzamide

Formula: C₁₃H₉ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 276.68

Ref: 54-OR1010391

GW9662

CAS: 22978-25-2

Formula: C₁₃H₁₉ClN₂O₃

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to yellow crystalline powder

Molecular weight: 276.68

Ref: 7W-GL4781

GW9662

CAS: 22978-25-2

2-Chloro-5-nitro-N-phenylbenzamide

Formula: C₁₃H₉ClN₂O₃

Purity: 98%

Molecular weight: 276.68

Ref: IN-DG132495

GW9662

CAS: 22978-25-2

GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!

Formula: C₁₃H₉ClN₂O₃

Purity: 98% - 99.98%

Color and Shape: White Solid

Molecular weight: 276.68

Ref: TM-T2260

2-Chloro-5-nitro-N-phenylbenzamide

CAS: 22978-25-2

Formula: C₁₃H₉ClN₂O₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 276.68

Ref: 10-F497827

2-Chloro-5-nitro-N-4-phenylbenzamide

Controlled Product

CAS: 22978-25-2

Applications A cell-permeable, selective and irreversible PPARγ antagonist (IC50 = 3.3 nM, 32 nM, and 2 µM for PPARγ, PPARα, and PPARδ, respectively). Reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10 µM, also acts as an agonist of human pregnane X receptor (PXR) and farnesoid X receptor (FXR). Does not activate liver X receptor-a (LXRa), retinoic acid receptor (RAR), retinoid X receptor-a (RXRa) and thyroid receptors a and b (TRa and TRb
References Huang, J.T., et al.: Nature, 400, 378 (1999), Wilson, T.M., et al.: J. Med. Chem., 43, 527 (2000), Leesnitzer, L.M., et al.: Biochemistry, 41, 6640 (2002)

Formula: C₁₃H₉ClN₂O₃

Color and Shape: Neat

Molecular weight: 276.68

Ref: TR-C374050

GW 9662

CAS: 22978-25-2

PPARγ antagonist

Formula: C₁₃H₉ClN₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 276.68 g/mol

Ref: 3D-FC20132