CAS 22990-19-8

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline

Description:

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is an organic compound characterized by its bicyclic structure, which includes a phenyl group attached to a tetrahydroisoquinoline framework. This compound features a nitrogen atom within a saturated ring system, contributing to its basicity and potential for forming various derivatives. It is typically a colorless to pale yellow liquid or solid, depending on its purity and form. The presence of the phenyl group enhances its lipophilicity, making it more soluble in organic solvents than in water. This compound is of interest in medicinal chemistry due to its structural similarity to various biologically active molecules, including alkaloids. It may exhibit pharmacological properties, such as analgesic or neuroprotective effects, although specific biological activities can vary. The compound's reactivity can be influenced by the presence of the nitrogen atom and the aromatic phenyl group, allowing for potential modifications in synthetic applications. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₅H₁₅N

InChI: InChI=1/C15H15N/c1-2-7-13(8-3-1)15-14-9-5-4-6-12(14)10-11-16-15/h1-9,15-16H,10-11H2

SMILES: c1ccc(cc1)C1c2ccccc2CCN1

Synonyms:

• 1,2,3,4-Tetrahydro-1-phenylisoquinoline
• Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-
• 1-Phenyl-1,2,3,4-Tetrahydroisochinoline

1-Phenyl-1,2,3,4-tetrahydroisoquinoline

CAS: 22990-19-8

Formula: C₁₅H₁₅N

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 209.29

Ref: 3B-P2056

Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-

CAS: 22990-19-8

Formula: C₁₅H₁₅N

Purity: 98%

Color and Shape: Solid

Molecular weight: 209.2863

Ref: IN-DA002LS1

rac-Solifenacin EP Impurity A

CAS: 22990-19-8

Formula: C₁₅H₁₅N

Color and Shape: White To Off-White Solid

Molecular weight: 209.29

Ref: 4Z-S-1852

1,2,3,4-Tetrahydro-1-Phenylisoquinoline

CAS: 22990-19-8

1,2,3,4-Tetrahydro-1-Phenylisoquinoline

Purity: 98%

Molecular weight: 209.29g/mol

Ref: 54-OR1009060

rac 1-Phenyl-1,2,3,4-tetrahydroisoquinoline

Controlled Product

CAS: 22990-19-8

Applications 1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a Solifenacin (S676700) intermediate. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline had been detected in parkinsonian human brain. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline maybe a candidate for endogenous MPTP-like neurotoxin since it is a structural analogue of MPTP which produces parkinsonism in humans.
References Kajita, M. et al.: J. Chrom. B Biomed. Appl., 669, 345 (1995);

Formula: C₁₅H₁₅N

Color and Shape: Neat

Molecular weight: 209.29

Ref: TR-P336920

Solifenacin Related Compound 24

CAS: 22990-19-8

Formula: C₁₅H₁₅N

Molecular weight: 209.28

Ref: ST-EA-CP-S9012

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline

CAS: 22990-19-8

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 209.29200744628906

Ref: 10-F029586

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline

CAS: 22990-19-8

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a synthetic compound which has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. This drug is racemized in the body and has been found to be effective against Parkinson's disease in rats. It is also an enantiomer that has industrial applications for the production of polyurethane foam insulation coatings.

Formula: C₁₅H₁₅N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 209.29 g/mol

Ref: 3D-IP14816