CAS 2304549-73-1

Formula: C16H14ClF3N4O2

InChI: InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)

InChI key: MITRKIWBJVJRAM-UHFFFAOYSA-N

SMILES: C1CN(C(=O)CN1C2=C(C(=O)NN=C2)Cl)CC3=CC=CC=C3C(F)(F)F

GFB-8438

CAS: 2304549-73-1

GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).

Formula: C₁₆H₁₄ClF₃N₄O₂

Purity: 99.58%

Color and Shape: Solid

Molecular weight: 386.76

Ref: TM-T11394

GFB-8438

CAS: 2304549-73-1

GFB-8438

Formula: C₁₆H₁₄ClF₃N₄O₂

Purity: 99.5%

Molecular weight: 386.76

Ref: 54-BUP09854

4-Chloro-5-(3-oxo-4-(2-(trifluoromethyl)benzyl)piperazin-1-yl)pyridazin-3(2H)-one

CAS: 2304549-73-1

4-Chloro-5-(3-oxo-4-(2-(trifluoromethyl)benzyl)piperazin-1-yl)pyridazin-3(2H)-one

Formula: C₁₆H₁₄ClF₃N₄O₂

Purity: 98%

Molecular weight: 386.76

Ref: IN-DG01172603

4-Chloro-5-[3-oxo-4-(2-trifluoromethyl-benzyl)-piperazin-1-yl]-2H-pyridazin-3-one

CAS: 2304549-73-1

Purity: 98%

Molecular weight: 386.7600098

Ref: 10-F864366

GFB-8438

CAS: 2304549-73-1

GFB-8438 is a molecule that is structurally similar to the non-selective cation channel blocker, amiloride. GFB-8438 blocks the uptake of ions from the cytoplasm into organelles and may be useful in treating virus infections and cancers. It has been shown to inhibit coronaviruses and other viruses that use ion channels for cellular entry. GFB-8438 also inhibits cation channels in cells, which are important for cell function, highlighting its potential as a cancer drug.

Formula: C₁₆H₁₄ClF₃N₄O₂

Purity: Min. 95%

Molecular weight: 386.75 g/mol

Ref: 3D-ESD54973