CAS 2306877-20-1

Formula: C31H36F2N8O4

InChI: InChI=1S/C31H36F2N8O4/c1-19-17-39(3)13-14-41(19)24-6-8-27(37-28(24)44-4)38-30-35-11-9-23(36-30)21-5-7-25(22(15-21)16-34)45-26-10-12-40(18-31(26,32)33)29(43)20(2)42/h5-9,11,15,19-20,26,42H,10,12-14,17-18H2,1-4H3,(H,35,36,37,38)/t19-,20-,26?/m1/s1

InChI key: ZYYSJDLMODJVDG-FUHTXCSMSA-N

SMILES: C[C@@H]1CN(CCN1C2=C(N=C(C=C2)NC3=NC=CC(=N3)C4=CC(=C(C=C4)OC5CCN(CC5(F)F)C(=O)[C@@H](C)O)C#N)OC)C

TBK1/IKKε-IN-6

CAS: 2306877-20-1

TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.

Formula: C₃₁H₃₆F₂N₈O₄

Color and Shape: Solid

Molecular weight: 622.678

Ref: TM-T39841