CAS 23313-80-6

Epitetracycline hydrochloride

Description:

Epitetracycline hydrochloride is a semi-synthetic derivative of tetracycline, classified as an antibiotic. It exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive and Gram-negative bacteria by inhibiting protein synthesis through binding to the 30S ribosomal subunit. This compound is characterized by its stability in acidic conditions, which enhances its bioavailability. Epitetracycline hydrochloride is typically administered orally and is known for its therapeutic applications in treating various infections, including respiratory and urinary tract infections. The hydrochloride form improves solubility in water, facilitating its use in pharmaceutical formulations. Additionally, it possesses anti-inflammatory properties, making it useful in treating conditions like acne. However, like other tetracyclines, it may cause side effects such as gastrointestinal disturbances and photosensitivity. It is important to note that the use of epitetracycline hydrochloride should be guided by susceptibility testing to avoid resistance development. Overall, this compound plays a significant role in modern medicine, particularly in the treatment of bacterial infections.

Formula: C₂₂H₂₄N₂O₈·ClH

InChI: InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15+,21+,22-;/m0./s1

InChI key: InChIKey=XMEVHPAGJVLHIG-DXDJYCPMSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl

Synonyms:

• Epitetracycline hydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4R,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4R,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4R-(4α,4aβ,5aβ,6α,12aβ)]-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, 4-epimer

4-EPITETRACYCLINE HYDROCHLORIDE CRS

CAS: 23313-80-6

4-EPITETRACYCLINE HYDROCHLORIDE CRS

Ref: 41-E0600000

Epitetracycline Hydrochloride

CAS: 23313-80-6

Tetracyclines and their derivatives; salts thereof

Formula: C₂₂H₂₄N₂O₈·HCl

Color and Shape: Yellow Powder

Molecular weight: 480.12994

Ref: 45-1237509

4-Epitetracycline hydrochloride

CAS: 23313-80-6

Formula: C₂₂H₂₅ClN₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 480.8955

Ref: IN-DA003LAX

PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol

Controlled Product

CAS: 101342-45-4, 14206-58-7, 179471-95-5, 2058-46-0, 23313-80-6, 24390-14-5, 41411-66-9, 64-72-2, 64-73-3, 64-75-5

Color and Shape: Colourless

Ref: 04-A30000035ME

4-Epitetracycline hydrochloride

Controlled Product

CAS: 23313-80-6

Formula: C₂₂H₂₄N₂O₈·ClH

Color and Shape: Neat

Molecular weight: 480.90

Ref: 04-C13179500

4-Epitetracycline Hydrochloride

Controlled Product

CAS: 23313-80-6

Formula: C₂₂H₂₄N₂O₈·ClH

Color and Shape: Neat

Molecular weight: 480.90

Ref: 86-MM0452.01

Lymecycline EP Impurity A

CAS: 23313-80-6

Formula: C₂₂H₂₄N₂O₈HCl

Molecular weight: 444.44 : 36.46

Ref: ST-EA-CP-L64001

4-epi-Tetracycline Hydrochloride

Controlled Product

CAS: 23313-80-6

Applications Metabolite of Tetracycline (T291400). This compound is a contaminant of emerging concern (CECs).
References Diana, J., et al.: J. Pharm. Biomed. Anal., 39, 523 (2005), Fritz, J., et al.: Food Chem., 105, 1297 (2007), Gratacos-Cubarsi, M., et al.: J. Agric. Food Chem., 55, 4610 (2007),

Formula: C₂₂H₂₄N₂O₈·ClH

Color and Shape: Yellow

Molecular weight: 480.90

Ref: TR-T291405

4-Epitetracycline hydrochloride

CAS: 23313-80-6

Epitetracycline is an epimer of the antibiotic tetracycline . Epimers of tetracycline form without catalysis and are considered degradation products. Epitetracycline has decreased activity as an antibiotic or a Tet repressor effector but may have stronger toxic effects in animals.

Formula: C₂₂H₂₅ClN₂O₈

Color and Shape: Solid

Molecular weight: 480.90

Ref: TM-T37965

4-Epitetracycline hydrochloride

CAS: 23313-80-6

4-Epitetracycline hydrochloride is a tetracycline antibiotic derivative, which is a secondary metabolite derived from bacterial sources, particularly Streptomyces species. It functions primarily by inhibiting protein synthesis in bacteria through binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the RNA-ribosome complex. This action hinders bacterial growth by interfering with vital processes necessary for bacterial survival and replication.

Formula: C₂₂H₂₅ClN₂O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 480.9 g/mol

Ref: 3D-AE22744