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CAS 23405-15-4

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benzoic acid N-hydroxysuccinimide ester

Description:
Benzoic acid N-hydroxysuccinimide ester, with the CAS number 23405-15-4, is a chemical compound commonly used in bioconjugation and peptide synthesis. This compound features a benzoic acid moiety linked to an N-hydroxysuccinimide (NHS) group, which is known for its ability to form stable amide bonds with primary amines. The NHS ester is particularly valuable in biochemical applications due to its reactivity and ability to facilitate the conjugation of biomolecules, such as proteins and peptides, without the need for harsh conditions. The compound is typically a white to off-white solid and is soluble in organic solvents like dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). Its reactivity allows for selective labeling and modification of biomolecules, making it a useful tool in drug development, diagnostics, and research. Safety precautions should be observed when handling this compound, as it may cause irritation to the skin and eyes.
Formula:C11H9NO4
InChI:InChI=1/C11H9NO4/c13-9-6-7-10(14)12(9)16-11(15)8-4-2-1-3-5-8/h1-5H,6-7H2
SMILES:c1ccc(cc1)C(=O)ON1C(=O)CCC1=O
Synonyms:
  • Bz-OSu
  • 1-(Benzoyloxy)Pyrrolidine-2,5-Dione
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