CAS 23496-41-5
:Peimine
Description:
Peimine is a chemical compound classified as an alkaloid, primarily derived from the plant species *Veratrum* (commonly known as false hellebore). It is known for its structural complexity, featuring a tetracyclic framework that contributes to its biological activity. Peimine exhibits a range of pharmacological effects, including potential anti-inflammatory and analgesic properties, which have garnered interest in medicinal chemistry. The compound interacts with various biological targets, influencing neurotransmitter systems and ion channels. Its solubility characteristics can vary, typically being more soluble in organic solvents than in water, which is common for many alkaloids. Due to its potent biological effects, peimine has been studied for its potential therapeutic applications, although it also requires careful handling due to its toxicity at higher concentrations. As with many natural products, the extraction and purification processes are crucial for obtaining peimine in a form suitable for research or pharmaceutical use. Overall, peimine represents a significant area of interest in both natural product chemistry and pharmacology.
Formula:C27H45NO3
InChI:InChI=1S/C27H45NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-25,29-31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,24-,25-,26+,27-/m0/s1
InChI key:InChIKey=IUKLSMSEHKDIIP-BZMYINFQSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@@](C3)([C@]5([C@](CC4)([C@](C)(O)[C@]6(N(C5)C[C@@H](C)CC6)[H])[H])[H])[H])[H])(C[C@H](O)[C@]1(C[C@@H](O)CC2)[H])[H])[H]
Synonyms:- (3Beta,5Alpha,6Alpha)-Cevane-3,6,20-Triol
- (3β,5α,6α)-Cevane-3,6,20-triol
- 5α-Cevane-3β,6α,20-triol
- Cevane-3,6,20-triol, (3β,5α,6α)-
- Dihydroisoimperialine
- Verticine
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Peimine
CAS:Formula:C27H45NO3Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:431.66Peimine (Standard)
CAS:Peimine (Standard) is a reference standard for research and analysis in studies involving Peimine. 1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.Formula:C27H45NO3Color and Shape:SolidMolecular weight:431.6511Peimine
CAS:Controlled ProductApplications Peimine is a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants.
References Zhou, J. et al.: J. Chrom. A., 1177, 126 (2008); Li, S. et al.: J. Chrom. A., 873, 221 (2000);Formula:C27H45NO3Color and Shape:NeatMolecular weight:431.65(3S,4aS,5S,6aS,6bS,8aS,9S,9aS,12S,15aS,15bR,16aS,16bR)-9,12,16b-Trimethyltetracosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinoline-3,5,9-triol
CAS:(3S,4aS,5S,6aS,6bS,8aS,9S,9aS,12S,15aS,15bR,16aS,16bR)-9,12,16b-Trimethyltetracosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinoline-3,5,9-triolFormula:C27H45NO3Purity:98%Molecular weight:431.65Peimine
CAS:Natural alkaloidFormula:C27H45NO3Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:431.66Peimine
CAS:Peimine is a bioactive alkaloid, which is derived from the Fritillaria species, a group of plants commonly found in East Asia. Fritillaria bulbs have been utilized in traditional medicine for centuries, particularly in Chinese medicine. Peimine's mode of action involves anti-inflammatory and antitussive activities, which are attributed to its ability to inhibit inflammatory cytokines and modulate signaling pathways within cells.
Purity:Min. 95%
