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CAS 2351149-20-5

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  • TGFβRII-IN-3
    Targetmol
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    TGFβRII-IN-3

    CAS:
    TGFβRII-IN-3 (Compound 2r) is a selective inhibitor of the TGFβ type II receptor (TGFβ RII) with an IC50 of 4.1 μM. It inhibits TGFβ signaling by promoting protein degradation of TGFβ RII. Additionally, TGFβRI-IN-7 can block the transition from endothelial to mesenchymal states and inhibit cell migration, making it useful for cancer research.
    Formula:C27H27F3N2O2
    Color and Shape:Solid
    Molecular weight:468.51

    Ref: TM-T209758

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