CAS 2365497-07-8

Formula: C30H35F3N6O3

InChI: InChI=1S/C30H35F3N6O3/c1-41-27-17-23(38-15-12-34-13-16-38)6-9-26(27)37-28-18-24(10-11-35-28)39-14-2-3-22(20-39)29(40)36-19-21-4-7-25(8-5-21)42-30(31,32)33/h4-11,17-18,22,34H,2-3,12-16,19-20H2,1H3,(H,35,37)(H,36,40)/t22-/m0/s1

InChI key: JQWJRFOFKDLCQB-QFIPXVFZSA-N

SMILES: COC1=C(C=CC(=C1)N2CCNCC2)NC3=NC=CC(=C3)N4CCC[C@@H](C4)C(=O)NCC5=CC=C(C=C5)OC(F)(F)F

ALK/ROS1-IN-1

CAS: 2365497-07-8

ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).

Formula: C₃₀H₃₅F₃N₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 584.63

Ref: TM-T10286