CAS 23672-07-3
:Levosulpiride
Description:
Levosulpiride is a substituted benzamide derivative primarily used as an antipsychotic and gastrointestinal motility agent. It acts as a selective dopamine D2 receptor antagonist, which contributes to its therapeutic effects in treating conditions such as schizophrenia and functional gastrointestinal disorders. The compound is characterized by its chiral nature, with the "levo" prefix indicating the specific enantiomer that exhibits the desired pharmacological activity. Levosulpiride is typically administered orally and is known for its relatively low side effect profile compared to other antipsychotics. Its solubility in water is moderate, and it is often formulated in various dosage forms, including tablets and oral solutions. The substance is also recognized for its potential to enhance gastric motility, making it useful in treating dyspeptic symptoms. As with any medication, the use of levosulpiride should be guided by a healthcare professional, considering its pharmacokinetics, potential interactions, and contraindications.
Formula:C15H23N3O4S
InChI:InChI=1/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
InChI key:InChIKey=BGRJTUBHPOOWDU-NSHDSACASA-N
SMILES:C(NC[C@H]1N(CC)CCC1)(=O)C2=C(OC)C=CC(S(N)(=O)=O)=C2
Synonyms:- (-)-5-Aminosulfonyl-N-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxy-Benzamide
- (-)-N-1-[Ethylpyrrolidin-2-Ylmethyl]-2-Methoxy-5-Sulfamoylbenzamide
- (-)-Sulpiride
- (S)-(-)-5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolinyl)methyl]
- (S)-(-)-5-Aminosulfonyl-N-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxybenzamide
- (S)-(-)-N-((1-Ethyl-2-Pyrrolidinyl)Methyl)-5-Sulfamoyl-O-Anisamide
- (S)-(-)-N-((1-Ethyl-2-Pyrrolidinyl)Methyl)-5-Sulfamoyl-O-Anisamide 5-(Aminosulfonyl)-N-((1-Ethyl-2-Pyrrolidinyl)Methyl)-2-Methoxy-Benzamid ( S-(-)-Benzamid
- (S)-(-)-Sulpiride
- (S)-(-)-Sulpiride, Vetranal
- 5-(Aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxybenzamide
- <span class="text-smallcaps">L</span>-Sulpiride
- Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, (S)-
- Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-
- Lesuride
- Levobren
- Levopraid
- Levopride
- Levosulpride
- N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-methoxy-5-sulfamoylbenzamide
- Rv-12309
- Rv-12309 S-(-)-N-(1-Ethyl-2-Pyrrolidinomethyl)-2-Methoxy-5-Sulfamoylebenzamide
- S(-)-Sulpiride Dopamine D1 Antagonis
- S-(-)-N-(1-Ethyl-2-Pyrrolidinomethyl)-2-Methoxy-5-Sulfamoylebenzamide
- Sulpid
- l-Sulpiride
- o-Anisamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-, (-)-
- s-(-)-sulpiride (S)-5-Aminosulfonyl-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
- LEVOSULPIRIDE/LEVOSULPRIDE
- (s)-(-)-o-anisamid
- LEVOSULPIRIDE
- Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-(9CI)
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(S)-(-)-Sulpiride
CAS:Formula:C15H23N3O4SPurity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:341.43Levosulpiride
CAS:Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.Formula:C15H23N3O4SPurity:98.20% - 99.88%Color and Shape:White SolidMolecular weight:341.43Levosulpiride
CAS:Formula:C15H23N3O4SPurity:98.0 - 102.0 %Color and Shape:White to off-white powderMolecular weight:341.43S-(-)-Sulpiride
CAS:Controlled ProductApplications Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.
References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),Formula:C15H23N3O4SColor and Shape:NeatMolecular weight:341.43Levopride
CAS:Applications Antipsychotic; antidepressant; antiemetic.
References Karolidis, D., et al.: Med. Chem., 6, 259 (2010), Cummings, D., et al.: J. Pharmacol. Exper. Ther., 335, 518 (2010),Formula:C15H23N3O4SColor and Shape:NeatMolecular weight:341.43(S)-N-((1-Ethylpyrrolidin-2-yl)methyl)-2-methoxy-5-sulfamoylbenzamide
CAS:Formula:C15H23N3O4SPurity:99+%Molecular weight:341.43Levosulpiride - Bio-X ™
CAS:Controlled ProductLevosulpiride is a pharmacological agent which binds to dopamine (D2) receptors in the brain and gastrointestinal tract. It is used both to treat conditions that cause abnormal movements for e.g. Parkinson's disease and tardive dyskinesia, and also as an antiemetic and to treat certain gastric disorders. Additional to acting as a dopamine receptor antagonist, Levosulpiride also binds to α1-acid glycoprotein and has been shown to have a concentration-dependent effect on serum prolactin levels, with higher doses leading to increased levels, as well as an effect on basic fibroblasts.
Formula:C15H23N3O4SPurity:(%) Min. 95%Color and Shape:PowderMolecular weight:341.43 g/mol
