CAS 23720-80-1

Nardosinone

Description:

Nardosinone is a natural sesquiterpene compound primarily derived from the plant Nardostachys jatamansi, commonly known as spikenard. It is characterized by its complex bicyclic structure, which contributes to its unique chemical properties. Nardosinone exhibits a range of biological activities, including anti-inflammatory, antimicrobial, and potential neuroprotective effects, making it of interest in pharmacological research. The compound is typically found in essential oils and extracts from the plant, and its presence is often associated with traditional medicinal practices. In terms of solubility, nardosinone is generally more soluble in organic solvents than in water, which is common for many terpenoids. Its molecular structure includes multiple functional groups that can participate in various chemical reactions, enhancing its potential applications in both natural product chemistry and therapeutic development. Overall, nardosinone represents a significant compound within the realm of natural products, with ongoing studies aimed at elucidating its full range of biological effects and potential uses in medicine.

Formula: C₁₅H₂₂O₃

InChI: InChI=1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1

InChI key: InChIKey=KXGHHSIMRWPVQM-JWFUOXDNSA-N

SMILES: C[C@@]12[C@]3([C@@](CC(=O)C1=CCC[C@H]2C)(OOC3(C)C)[H])[H]

Synonyms:

• (3aR,9R,9aR,9bS)-1,1,9,9a-tetramethyl-1,3a,4,7,8,9,9a,9b-octahydro-5H-naphtho[2,1-c][1,2]dioxol-5-one
• (3aR,9R,9aR,9bS)-1,3a,4,7,8,9,9a,9b-Octahydro-1,1,9,9a-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one
• 5H-Naphtho[2,1-c][1,2]dioxol-5-one, 1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, (3aR,9R,9aR,9bS)-
• 5H-Naphtho[2,1-c][1,2]dioxol-5-one, 1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, [3aR-(3aα,9α,9aα,9bα)]-
• Nardosinon
• Nardosinone

NARDOSINONE

CAS: 23720-80-1

Formula: C₁₅H₂₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 250.3334

Ref: IN-DA00C4G3

Nardosinone

CAS: 23720-80-1

Nardosinone

Purity: ≥98%

Molecular weight: 250.33g/mol

Ref: 54-BUP05640

Nardosinone

CAS: 23720-80-1

Nardosinone

Purity: 98%

Molecular weight: 250.33g/mol

Ref: 54-OR1024412

Nardosinone

CAS: 23720-80-1

Formula: C₁₅H₂₂O₃

Molecular weight: 250.34

Ref: 7W-GY9891

Nardosinone

CAS: 23720-80-1

Nardosinone is an enhancer of nerve growth factor and possesses a wide range of pharmacological effects, including sedative, adaptogen-like, anti-depressive, anti-leukemic, anti-tumorous, and anti-trypanosomal activities. It has a wide spectrum of targets including PI3K,Akt,MEK,ERK, PKA, MAPK.

Formula: C₁₅H₂₂O₃

Purity: 95%~99%

Molecular weight: 250.338

Ref: BP-BP0980

Nardosinone

CAS: 23720-80-1

Nardosinone inhibits H9c2 cell hypertrophy, protects neurons from OGD, and boosts neurite outgrowth by modifying key signaling pathways.

Formula: C₁₅H₂₂O₃

Purity: 98.82% - 99%

Color and Shape: Solid

Molecular weight: 250.33

Ref: TM-T6S1740

Nardosinone

CAS: 23720-80-1

Oxygen-heterocyclic compound

Formula: C₁₅H₂₂O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Crystals

Molecular weight: 250.34

Ref: 5G-83526

NARDOSINONE

CAS: 23720-80-1

Purity: ≥98%

Molecular weight: 250.3379974

Ref: 10-F859800

Nardosinone

Controlled Product

CAS: 23720-80-1

Applications Nardosinone reduces neuronal injury and protects H9c2 cardiac cells from angiotensin II-induced hypertrophy which may give rise to heart failure. Enhancer of nerve growth factor (NGF).
References Du, M. et al.: J. Huazhong Uni. Sci. Tech. Med. Serv., 33, 822 (2013); Li, P. et al.: Dev. Brain Res., 145, 177 (2003);

Formula: C₁₅H₂₂O₃

Color and Shape: White To Off-White

Molecular weight: 250.33

Ref: TR-N378930

Nardosinone

Controlled Product

CAS: 23720-80-1

Nardosinone is a secoiridoid compound, which is a natural product derived from the roots of the plant Nardostachys jatamansi, commonly known as spikenard. The source of Nardosinone is a flowering plant that is native to the Himalayan region and has been traditionally used in Ayurvedic medicine for its therapeutic properties. The mode of action of Nardosinone involves modulation of neurotransmitter systems, inhibition of neuroinflammation, and protection against oxidative damage, contributing to its neuroprotective effects. Nardosinone exhibits potential applications in the treatment of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, due to its ability to improve cognitive function and mitigate neuronal damage. Additionally, it is being investigated for its potential role in mood regulation and anti-anxiety effects. Given its intriguing pharmacological profile, Nardosinone is the subject of ongoing research aimed at understanding its comprehensive mechanisms and potential therapeutic benefits in neuroscience.

Formula: C₁₅H₂₂O₃

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 250.33 g/mol

Ref: 3D-FN73909