CAS 23735-43-5

(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate

Description:

(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate, with CAS number 23735-43-5, is a chemical compound characterized by its dioxolane structure, which features a five-membered ring containing two oxygen atoms. This compound is typically used in organic synthesis and may serve as a protecting group for alcohols due to the presence of the hydroxymethyl group. The p-toluenesulfonate moiety enhances its reactivity, making it useful in various chemical transformations. The stereochemistry indicated by (S)-(+)- suggests that it has a specific spatial arrangement, which can influence its biological activity and interactions. This compound is likely to be soluble in organic solvents and may exhibit moderate stability under standard laboratory conditions. Its applications may extend to pharmaceuticals or fine chemicals, where selective reactivity is essential. As with many chemical substances, proper handling and safety precautions are necessary due to potential hazards associated with its use.

Formula: C₁₃H₁₈O₅S

InChI: InChI=1/C13H18O5S/c1-10-4-6-12(7-5-10)19(14,15)17-9-11-8-16-13(2,3)18-11/h4-7,11H,8-9H2,1-3H3/t11-/m0/s1

SMILES: Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1COC(C)(C)O1

Synonyms:

• L-alpha,beta-isopropylidene glycerol-gamma-tosylate
• (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
• (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate
• (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
• (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl 4-Methylbenzenesulfonate
• [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 286.3440

Ref: IN-DA003CKP

(S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate

CAS: 23735-43-5

(S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate

Purity: 99%

Color and Shape: White Low-Melting Solid

Molecular weight: 286.34g/mol

Ref: 54-OR315279

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 286.34

Ref: 3B-D2550

Landiolol Impurity 28

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Molecular weight: 286.34

Ref: 4Z-L-100029

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Purity: 98%

Color and Shape: Crystalline

Molecular weight: 286.34

Ref: 10-F050906

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate

Controlled Product

CAS: 23735-43-5

Applications (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.
References Dams, I., et. al.: Tetrahedrom, 69, 1634 (2013); Koeberle, S.C., et. al.: J. Med. Chem., 55, 5868 (2012)

Formula: C₁₃H₁₈O₅S

Color and Shape: Neat

Molecular weight: 286.34

Ref: TR-D469555