CAS 23735-43-5

(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate

Formula: C₁₃H₁₈O₅S

InChI: InChI=1/C13H18O5S/c1-10-4-6-12(7-5-10)19(14,15)17-9-11-8-16-13(2,3)18-11/h4-7,11H,8-9H2,1-3H3/t11-/m0/s1

SMILES: Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1COC(C)(C)O1

Synonyms:

• L-alpha,beta-isopropylidene glycerol-gamma-tosylate
• (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
• (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate
• (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
• (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl 4-Methylbenzenesulfonate
• [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate

(S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate

CAS: 23735-43-5

(S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate

Formula: C₁₃H₁₈O₅S

Purity: 99%

Color and Shape: White Solid-Low Melt

Molecular weight: 286.34402

Ref: 54-OR315279

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 286.3440

Ref: IN-DA003CKP

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 286.34

Ref: 3B-D2550

Landiolol Impurity 28

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Molecular weight: 286.34

Ref: 4Z-L-100029

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate

CAS: 23735-43-5

Formula: C₁₃H₁₈O₅S

Purity: 98%

Color and Shape: Crystalline

Molecular weight: 286.34

Ref: 10-F050906

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate

Controlled Product

CAS: 23735-43-5

Applications (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.
References Dams, I., et. al.: Tetrahedrom, 69, 1634 (2013); Koeberle, S.C., et. al.: J. Med. Chem., 55, 5868 (2012)

Formula: C₁₃H₁₈O₅S

Color and Shape: Neat

Molecular weight: 286.34

Ref: TR-D469555

(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate

CAS: 23735-43-5

(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate

Formula: C₁₃H₁₈O₅S

Purity: 95%

Molecular weight: 286.34

Ref: IN-DG48229