CAS 2375595-72-3

Formula: C19H22Cl2N6OS

InChI: InChI=1S/C19H20N6OS.2ClH/c1-24-5-7-25(8-6-24)11-2-3-13-14(10-11)22-17(21-13)15-16(20)12-4-9-27-19(12)23-18(15)26;;/h2-4,9-10H,5-8H2,1H3,(H,21,22)(H3,20,23,26);2*1H

InChI key: XESGZTINOLHKPH-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(NC4=O)SC=C5)N.Cl.Cl

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

CAS: 2375595-72-3

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

Formula: C₁₉H₂₂Cl₂N₆OS

Purity: 95%

Molecular weight: 453.39

Ref: 54-OR1122142

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

CAS: 2375595-72-3

Formula: C₁₉H₂₂Cl₂N₆OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 453.3886

Ref: IN-DA01X79M

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

CAS: 2375595-72-3

Formula: C₁₉H₂₂Cl₂N₆OS

Purity: 99%

Molecular weight: 453.39

Ref: IN-DG01722107

HPK1-IN-2 dihydrochloride

CAS: 2375595-72-3

HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 µM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 µM, and Flt3 kinase activity, with an IC 50 of less than 0.05 µM [1].

Formula: C₁₉H₂₂Cl₂N₆OS

Color and Shape: Solid

Molecular weight: 453.39

Ref: TM-T84714