CAS 2378801-85-3

Formula: C45H45BrN6O10S

InChI: InChI=1S/C45H45BrN6O10S/c46-27-11-13-28(14-12-27)63-35-17-15-32-39-29(35)5-3-6-30(39)42(57)51(43(32)58)22-19-48-36(53)9-1-2-10-37(54)49-21-24-62-26-25-61-23-20-47-33-8-4-7-31-40(33)45(60)52(44(31)59)34-16-18-38(55)50-41(34)56/h3-8,11-15,17,34,47H,1-2,9-10,16,18-26H2,(H,48,53)(H,49,54)(H,50,55,56)

InChI key: IUSLKFLLLNNOGR-UHFFFAOYSA-N

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=C6C(=C(C=C5)SC7=CC=C(C=C7)Br)C=CC=C6C4=O

N1-(2-(6-((4-Bromophenyl)thio)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-N6-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)adipamide

CAS: 2378801-85-3

N1-(2-(6-((4-Bromophenyl)thio)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-N6-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)adipamide

Formula: C₄₅H₄₅BrN₆O₁₀S

Purity: 98%

Molecular weight: 941.86

Ref: 54-OR1073784

PROTAC Bcl2 degrader-1

CAS: 2378801-85-3

PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).

Formula: C₄₅H₄₅BrN₆O₁₀S

Purity: 98%

Color and Shape: Solid

Molecular weight: 941.84

Ref: TM-T10485

PROTAC Bcl2 degrader-1

CAS: 2378801-85-3

Formula: C₄₅H₄₅BrN₆O₁₀S

Purity: 98.78%

Molecular weight: 941.842

Ref: IN-DA01NAW5

Mcl-1/Bcl-2 PROTAC compound C5

CAS: 2378801-85-3

N1-(2-(6-((4-Bromophenyl)thio)-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)ethyl)-N6-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)adipamide

Formula: C₄₅H₄₅BrN₆O₁₀S

Purity: 98%

Molecular weight: 941.84

Ref: IN-DG01150498

Protac bcl2 degrader-1

CAS: 2378801-85-3

Protac BCL2 Degrader-1 is a recombinant antibody that binds to human bcl2 and degrades it. It can be used as a research tool in cell biology, peptides, pharmacology, and other fields. Protac BCL2 Degrader-1 has shown to be an activator of ion channels and receptor interactions. It also has been shown to be a ligand for the following: GPCR, beta-adrenergic receptors, serotonin receptors, muscarinic receptors, nicotinic acetylcholine receptors. Protac BCL2 Degrader-1 is also known as CAS No. 2378801-85-3.

Formula: C₄₅H₄₅BrN₆O₁₀S

Purity: Min. 95%

Molecular weight: 941.8 g/mol

Ref: 3D-DVD80185