CAS 2380321-50-4

Formula: C22H28ClFN6O4S

InChI: InChI=1S/C22H28ClFN6O4S/c1-11(2)30-17-8-13(7-15(24)20(17)27-21(30)12(3)31)19-14(23)9-25-22(28-19)26-16-5-6-29(10-18(16)32)35(4,33)34/h7-9,11-12,16,18,31-32H,5-6,10H2,1-4H3,(H,25,26,28)/t12-,16-,18-/m1/s1

InChI key: KSCSDVHAZVSGAW-XHBKTUGNSA-N

SMILES: C[C@H](C1=NC2=C(N1C(C)C)C=C(C=C2F)C3=NC(=NC=C3Cl)N[C@@H]4CCN(C[C@H]4O)S(=O)(=O)C)O

CDK4/6-IN-5

CAS: 2380321-50-4

CDK4/6-IN-5 inhibits CDK4/6; Ki: 0.2 nM (CDK4/D1) & 4.4 nM (CDK6/D3). (WO2019207463A1, A93)

Formula: C₂₂H₂₈ClFN₆O₄S

Color and Shape: Solid

Molecular weight: 527.01

Ref: TM-T39956