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CAS 2381-85-3

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Nile Blue

Description:
Nile Blue, with the CAS number 2381-85-3, is a synthetic dye belonging to the class of phenothiazine derivatives. It is primarily known for its vibrant blue color and is often used in biological staining applications, particularly in microscopy to visualize cellular structures. Nile Blue exhibits distinct characteristics, including its ability to intercalate with nucleic acids, making it useful for differentiating between viable and non-viable cells. The dye is soluble in organic solvents and has limited solubility in water, which can influence its application in various experimental settings. Its fluorescence properties are also notable, as it can emit light upon excitation, allowing for enhanced imaging techniques. Additionally, Nile Blue has been studied for its potential applications in photodynamic therapy due to its ability to generate reactive oxygen species upon light activation. However, safety considerations must be taken into account, as with many synthetic dyes, due to potential toxicity and environmental impact. Overall, Nile Blue is a versatile compound with significant utility in both research and clinical settings.
Formula:C20H20N3O·Cl
InChI:InChI=1S/C20H20N3O.ClH/c1-3-23(4-2)13-9-10-17-18(11-13)24-19-12-16(21)14-7-5-6-8-15(14)20(19)22-17;/h5-12H,3-4,21H2,1-2H3;1H/q+1;/p-1
InChI key:InChIKey=XJCPMUIIBDVFDM-UHFFFAOYSA-M
SMILES:NC1=C2C(=C3C([O+]=C4C(=N3)C=CC(N(CC)CC)=C4)=C1)C=CC=C2.[Cl-]
Synonyms:
  • Nile Blue
  • C.I. Basic Blue 12
  • Benzo[a]phenoxazin-7-ium, 5-amino-9-(diethylamino)-, chloride
  • Benzo[a]phenoxazin-7-ium, 5-amino-9-(diethylamino)-, chloride (1:1)
  • C.I. 51180
Found 8 products.