CAS 23981-80-8
:(±)-Naproxen
Description:
(±)-Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It belongs to the propionic acid class of NSAIDs and is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins involved in inflammation and pain signaling. The substance is a racemic mixture, meaning it contains equal parts of its two enantiomers, which can exhibit different pharmacological effects. (±)-Naproxen is typically administered in its sodium salt form for enhanced solubility and absorption. It has a relatively long half-life, allowing for twice-daily dosing in therapeutic applications. Common side effects may include gastrointestinal discomfort, headache, and dizziness, while more serious risks involve cardiovascular and gastrointestinal complications. The compound is also known for its anti-inflammatory properties, making it effective in treating conditions such as arthritis and tendinitis. Its chemical structure includes a naphthalene ring, contributing to its lipophilicity and overall pharmacokinetic profile.
Formula:C14H14O3
InChI:InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)
InChI key:InChIKey=CMWTZPSULFXXJA-UHFFFAOYSA-N
SMILES:C(C(O)=O)(C)C1=CC2=C(C=C(OC)C=C2)C=C1
Synonyms:- (RS)-Naproxen
- (±)-2-(6-Methoxy-2-naphthalenyl)propionic acid
- (±)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
- (±)-Naproxen
- 2-(6-Methoxy-2-naphthyl)propanoic acid
- 2-(6-Methoxynaphthalen-2-yl)propanoic acid
- 2-(6-Methoxynaphthalen-2-yl)propionic acid
- 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-
- 6-Methoxy-2-naphthyl-α-methylacetic acid
- <span class="text-smallcaps">D</smallcap><smallcap>L</span>-2-(6-Methoxy-2-naphthyl)propionic acid
- <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Naproxen
- DL-Naproxen
- Racemic Naproxen
- α-(6-Methoxy-2-naphthyl)propionic acid
- See more synonyms
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Found 13 products.
(±)-Naproxen
CAS:Formula:C14H14O3Purity:>98.0%(GC)(T)Color and Shape:White to Light red to Green powder to crystalMolecular weight:230.26(+/-)-2-(6-Methoxy-2-naphthyl)propionic acid
CAS:Formula:C14H14O3Purity:98%Color and Shape:SolidMolecular weight:230.25922-(6-Methoxynaphthalen-2-Yl)Propanoic Acid
CAS:2-(6-Methoxynaphthalen-2-Yl)Propanoic AcidPurity:98%Molecular weight:230.26g/molrac-Naproxen
CAS:<p>Applications An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Formula:C14H14O3Color and Shape:NeatMolecular weight:230.262-(6-Methoxy-2-naphthyl)propionic acid
CAS:Formula:C14H14O3Purity:97%Color and Shape:Solid, Very pale yellow to pale reddish yellow powderMolecular weight:230.263rac-Naproxen-13C3
CAS:Controlled ProductFormula:C3C11H14O3Color and Shape:NeatMolecular weight:233.237rac-Naproxen
CAS:<p>Naproxen is a non-steroidal anti-inflammatory drug that is used to treat pain, fever, and inflammation. It is an analgesic and antipyretic agent. Naproxen has been shown to have a high affinity for copper chloride, which may be due to the formation of an amide bond. The reaction mechanism of naproxen's inhibition of prostaglandin synthesis in bacteria has been investigated using x-ray diffraction data from bacterial strains and human serum. Naproxen also has inhibitory properties on the reaction solution in vitro and enhances the toxicity studies with isooctane in vivo.</p>Formula:C14H14O3Purity:(%) Min. 95%Color and Shape:White/Off-White SolidMolecular weight:230.26 g/molRacemic Naproxen
CAS:Racemic Naproxen is a biochemical substance.Formula:C14H14O3Purity:98%Color and Shape:Crystals From Acetone-Hexane White SolidMolecular weight:230.26
