CAS 23981-80-8: (±)-Naproxen
Description:(±)-Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It belongs to the propionic acid class of NSAIDs and is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins involved in inflammation and pain signaling. The substance is a racemic mixture, meaning it contains equal parts of its two enantiomers, which can exhibit different pharmacological effects. (±)-Naproxen is typically administered in its sodium salt form for enhanced solubility and absorption. It has a relatively long half-life, allowing for twice-daily dosing in therapeutic applications. Common side effects may include gastrointestinal discomfort, headache, and dizziness, while more serious risks involve cardiovascular and gastrointestinal complications. The compound is also known for its anti-inflammatory properties, making it effective in treating conditions such as arthritis and tendinitis. Its chemical structure includes a naphthalene ring, contributing to its lipophilicity and overall pharmacokinetic profile.
Formula:C14H14O3
InChI:InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)
InChI key:InChIKey=CMWTZPSULFXXJA-UHFFFAOYSA-N
SMILES:O=C(O)C(C1=CC=C2C=C(OC)C=CC2=C1)C
- Synonyms:
- (RS)-Naproxen
- (±)-2-(6-Methoxy-2-naphthalenyl)propionic acid
- (±)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
- (±)-Naproxen
- 2-(6-Methoxy-2-naphthyl)propanoic acid
- 2-(6-Methoxynaphthalen-2-yl)propanoic acid
- 2-(6-Methoxynaphthalen-2-yl)propionic acid
- 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-
- 6-Methoxy-2-naphthyl-α-methylacetic acid
- <span class="text-smallcaps">D</smallcap><smallcap>L</span>-2-(6-Methoxy-2-naphthyl)propionic acid
- See more synonyms
- <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Naproxen
- DL-Naproxen
- Racemic Naproxen
- α-(6-Methoxy-2-naphthyl)propionic acid
- 2-(6-Methoxy-2-naphthyl)propionic acid

(±)-Naproxen
Ref: 3B-M1220
5g | 63.00 € | ||
25g | 212.00 € |

Ref: 41-Y0000399
10mg | 115.00 € |

(+/-)-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID
- Pharmaceutical Standards
- Anti-inflammatory
- Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
- Enzyme Activators and Inhibitors
- See more categories
- APIs for research and impurities
- Enzymes
- Immunology and Inflammation
- Cyclooxygenase (COX) Inhibitors
- Other Inhibitors
- Biochemicals and Reagents
- Cellular and Molecular Biology
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)
Ref: IN-DA00BBNZ
1g | 24.00 € | ||
5g | 53.00 € | ||
10g | 77.00 € | ||
25g | 115.00 € | ||
100g | 264.00 € |

Ref: 4Z-N-2339
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |

Ref: 54-OR1009794
1g | 32.00 € | ||
5g | 38.00 € | ||
25g | 154.00 € | ||
100g | 441.00 € |

Racemic Naproxen
Ref: TM-T20667
Undefined size | To inquire |

rac-Naproxen
Controlled ProductRef: 86-MM0152.19
25mg | 673.00 € | ||
100mg | 1,253.00 € |

2-(6-Methoxy-2-naphthyl)propionic acid
Ref: 10-F066541
1g | 24.00 € | ||
5g | 47.00 € | ||
10g | 71.00 € | ||
25g | 150.00 € |

rac-Naproxen
Ref: TR-N377526
1g | 114.00 € | ||
5g | 216.00 € | ||
25g | 511.00 € |

rac-Naproxen-13C3
Controlled ProductRef: TR-N377529
50mg | 14,422.00 € |

rac-Naproxen
Ref: 3D-FN27551
5g | 199.00 € | ||
10g | 318.00 € | ||
25g | 448.00 € | ||
50g | 664.00 € | ||
100g | 1,006.00 € |