TLR7 agonist 17, identified by its CAS number 2410517-32-5, is a synthetic compound that acts as an agonist for Toll-like receptor 7 (TLR7). TLR7 is a pattern recognition receptor that plays a crucial role in the immune system by recognizing single-stranded RNA, which is often associated with viral infections. The activation of TLR7 by agonists like TLR7 agonist 17 can enhance the immune response, making it a potential candidate for therapeutic applications in infectious diseases and cancer immunotherapy. This compound is characterized by its ability to stimulate the production of pro-inflammatory cytokines and type I interferons, which are vital for antiviral defense. Additionally, TLR7 agonists are being explored for their potential in vaccine adjuvants, as they can boost the efficacy of vaccines by promoting a robust immune response. The specific chemical structure and properties of TLR7 agonist 17 contribute to its biological activity, making it a subject of interest in pharmaceutical research and development.

TLR7 agonist 17

2410517-32-5: TLR7 agonist 17, identified by its CAS number 2410517-32-5, is a synthetic compound that acts as an agonist for Toll-like receptor 7 (TLR7). TLR7 is a pattern recognition receptor that plays a crucial role in the immune system by recognizing single-stranded RNA, which is often associated with viral infections. The activation of TLR7 by agonists like TLR7 agonist 17 can enhance the immune response, making it a potential candidate for therapeutic applications in infectious diseases and cancer immunotherapy. This compound is characterized by its ability to stimulate the production of pro-inflammatory cytokines and type I interferons, which are vital for antiviral defense. Additionally, TLR7 agonists are being explored for their potential in vaccine adjuvants, as they can boost the efficacy of vaccines by promoting a robust immune response. The specific chemical structure and properties of TLR7 agonist 17 contribute to its biological activity, making it a subject of interest in pharmaceutical research and development.

<p>TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].</p>

CAS 2410517-32-5

TLR7 agonist 17

TLR7 agonist 17

Ref: TM-T87535