CAS 2411440-41-8

L-Arginine, N2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-2-thienyl]carbonyl]-

Description:

L-Arginine, N2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-2-thienyl]carbonyl]- is a synthetic compound that features a complex structure incorporating both amino acid and thienyl moieties. As a derivative of L-arginine, it retains the basic properties of amino acids, including the presence of an amino group (-NH2) and a carboxyl group (-COOH), which contribute to its solubility in water and potential biological activity. The compound's thienyl group, along with the bis(4-chlorophenyl)methyl substituent, suggests potential interactions with biological targets, possibly influencing its pharmacological properties. The presence of chlorinated phenyl groups may enhance lipophilicity, affecting its distribution and metabolism in biological systems. This compound may be of interest in medicinal chemistry for its potential therapeutic applications, although specific biological activities and mechanisms would require further investigation. As with many synthetic compounds, safety and toxicity profiles should be assessed before any practical application.

Formula: C₂₅H₂₆Cl₂N₄O₃S

InChI: InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1

InChI key: OHRIKWUZKGNQKQ-IBGZPJMESA-N

SMILES: CC1=C(SC(=C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

Synonyms:

• 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride
• L-Arginine, N2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-2-thienyl]carbonyl]-
• JR14a
• (S)-2-(5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carboxamido)-5-guanidinopentanoic acid

(S)-2-(5-(Bis(4-Chlorophenyl)Methyl)-3-Methylthiophene-2-Carboxamido)-5-Guanidinopentanoic Acid

CAS: 2411440-41-8

(S)-2-(5-(Bis(4-Chlorophenyl)Methyl)-3-Methylthiophene-2-Carboxamido)-5-Guanidinopentanoic Acid

Formula: C₂₅H₂₆Cl₂N₄O₃S

Purity: 95%

Molecular weight: 533.47

Ref: 54-OR1023322

JR14a

CAS: 2411440-41-8

JR14a

Formula: C₂₅H₂₆Cl₂N₄O₃S

Purity: 99.5%

Molecular weight: 533.47

Ref: 54-BUP03473

(S)-2-(5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carboxamido)-5-guanidinopentanoic acid

CAS: 2411440-41-8

Formula: C₂₅H₂₆Cl₂N₄O₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 533.4699

Ref: IN-DA0201XE

JR14a

CAS: 2411440-41-8

JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.

Formula: C₂₅H₂₆Cl₂N₄O₃S

Purity: 99.76% - 99.96%

Color and Shape: Solid

Molecular weight: 533.47

Ref: TM-T9316

(S)-2-(5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carboxamido)-5-guanidinopentanoic acid

CAS: 2411440-41-8

(S)-2-(5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carboxamido)-5-guanidinopentanoic acid

Formula: C₂₅H₂₆Cl₂N₄O₃S

Purity: 95%

Molecular weight: 533.47

Ref: IN-DG01459297

(S)-2-(5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carboxamido)-5-guanidinopentanoic acid

CAS: 2411440-41-8

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 533.4699707

Ref: 10-F868484

JR14a

CAS: 2411440-41-8

JR14a is an analog inhibitor of protein kinases, which has shown promising results in the treatment of cancer. It is derived from indirubin, a natural compound found in Chinese urine that has been used for centuries in traditional medicine. JR14a specifically targets tumor cells and induces apoptosis, or programmed cell death, thereby inhibiting the growth and spread of cancer cells. This anticancer drug works by inhibiting protein kinases involved in cellular signaling pathways that regulate cell growth and division. JR14a has shown potential as a therapeutic agent for various types of cancer, including breast, lung, and colon cancer. Its ability to selectively target cancer cells without affecting healthy cells makes it a promising candidate for the development of new anticancer drugs.

Formula: C₂₅H₂₆Cl₂N₄O₃S

Purity: Min. 95%

Molecular weight: 533.5 g/mol

Ref: 3D-LWD44041