CAS 2414373-55-8

Formula: C22H25ClN8O

InChI: InChI=1S/C22H25ClN8O/c1-15(32)26-16-4-3-5-17(12-16)27-21-19(23)14-25-22(29-21)28-20-7-6-18(13-24-20)31-10-8-30(2)9-11-31/h3-7,12-14H,8-11H2,1-2H3,(H,26,32)(H2,24,25,27,28,29)

InChI key: GVJLKAACQAJVQS-UHFFFAOYSA-N

SMILES: CC(=O)NC1=CC=CC(=C1)NC2=NC(=NC=C2Cl)NC3=NC=C(C=C3)N4CCN(CC4)C

CDK6/9-IN-1

CAS: 2414373-55-8

CDK6/9-IN-1, an oral dual inhibitor of CDK6/9, has IC50s of 40.5nM (CDK6) and 39.5nM (CDK9).

Formula: C₂₂H₂₅ClN₈O

Color and Shape: Solid

Molecular weight: 452.95

Ref: TM-T40047